AICAr (5-amino-4-imidazolecarboxamide riboside, also called Acadesine) has been found to inhibit cell proliferation and has cytotoxic potential for childhood acute lymphoblastic leukemia (ALL) cells. Much of the drug's cytotoxic ...
Jan 31, 2019
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Search for a description of "p53" and it becomes clear that this human protein is widely known for its cancer-fighting benefits, leading to its renown as "the guardian of the genome."
Jan 31, 2019
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The concept sounds simple, but understanding the process has been elusive: Cut off the nutrient supply to suppress the growth of tumors.
Jan 31, 2019
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Of all gastrointestinal cancers, pancreatic cancer is one of the most aggressive. Because of this, it has a very low 5-year survival rate of just 5% and a median survival time below 6 months. Additionally, treatment is difficult, ...
Jan 24, 2019
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Sechenov University researchers and German colleagues report a highly sensitive, painless method for diagnosing kidney cancer. This method is based on measuring of the immune response to arrestin-1, a retina protein that ...
Jan 21, 2019
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In laboratory experiments, UC San Francisco researchers successfully beat back the growth of aggressive liver cancers using a surprising new approach. Traditionally, targeted cancer therapies aim to disable proteins borne ...
Jan 14, 2019
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Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and ...
Jan 10, 2019
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The spread of invasive cancer cells from a tumor's original site to distant parts of the body is known as metastasis. It is the leading cause of death in people with cancer. In a paper published online in iScience, University ...
Dec 5, 2018
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Researchers at the Mainz University Medical Center have discovered a new signal pathway employed by skin cancer cells to avoid attack by the immune system. In an animal model and through analysis of human tissue samples, ...
Nov 29, 2018
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Two patients with the same kind of tumor can have very different experiences. One patient's cancer may progress quickly while the other grows slowly. Treatments may shrink tumors or have no effect at all. And some patients ...
Sep 11, 2018
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