Oncology & Cancer

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Oncology & Cancer

Curry spice component may help slow prostate tumor growth

Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from researchers at Jefferson's ...

Medical research

Tumors' mechanical properties affect protein production

Tissues stiffen with age, poor diet, disease and for natural reasons, and when they do, a new study shows, proteins produced by such cells can be altered, which in turn affects downstream processes.

Oncology & Cancer

A stealthy way to combat tumors

Under the right circumstances, the body's T cells can detect and destroy cancer cells. However, in most cancer patients, T cells become disarmed once they enter the environment surrounding a tumor. 

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