Oncology & Cancer

Drug candidate kills cancer cells through overstimulation

A drug candidate that overstimulates proteins crucial for tumor growth shows promise as a new strategy to treat a wide range of cancers. The demands of rapid cell division put a strain on cancer cells, and the approach works ...

Oncology & Cancer

Team finds key to common cancer pathway

Scientists have long known that the protein p53, when mutated, is a critical factor in the onset of many different kinds of cancer. In its unmutated form, however, it is known to protect against cancer.

Oncology & Cancer

PGK1 protein promotes brain tumor formation and cancer metabolism

PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. ...

Oncology & Cancer

First-in-class targeted microRNA therapy slows cancer tumor growth

A new cancer therapy developed by Purdue University researchers attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division. As reported in Oncogene, tumors treated with the ...

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