Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers ...
Dec 7, 2020
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Vestibular schwannomas, more commonly known as acoustic neuromas, are benign brain tumors that develop on the balance (vestibular) and hearing or auditory nerves leading from the inner ear to the brain. These tumors are rare ...
Jul 22, 2020
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The experimental oncolytic adenovirus telomelysin (OBP-301) in combination with radiotherapy was safe and showed early clinical efficacy in vulnerable patients with esophageal cancer, according to results from a phase I clinical ...
Apr 2, 2019
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It's one of the first questions asked by many newly-diagnosed cancer patients—"What are my chances of beating this?" Often there is no clear answer, with survival rates differing widely depending on the cancer stage and ...
Jan 10, 2019
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While many cancer therapies initially can be very successful, tumors often return and spread when remaining cancer cells develop resistance to treatment. To combat this tendency, Frédéric Thomas of the French National Centre ...
Oct 2, 2018
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Many clinical trials for breast cancer fail to give clear answers on the efficacy of new therapies, despite enrolling thousands of patients and painstakingly tracking their outcomes for years. Now Yale Cancer Center (YCC) ...
Jan 25, 2018
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Metastatic or castrate-resistant prostate cancer can spread to the bone in certain patients. While several new treatments are available, they can have a difficult time reaching the bone and can result in missing the metastatic ...
Nov 13, 2017
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Tumor shrinkage is not the only measure of a successful anti-cancer therapy. A University of Colorado Cancer Center article published in the journal Frontiers in Oncology describes a promising alternative: metabolic imaging. ...
Aug 9, 2016
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An existing cancer immunotherapy drug reduces tumor size in some types of rare connective tissue cancers, called sarcomas, report researchers at the University of Pittsburgh Cancer Institute (UPCI). Additional analyses of ...
Jun 6, 2016
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(HealthDay)—The risks of developing an ipsilateral breast event (IBE) and an invasive IBE increased over time for patients with ductal carcinoma in situ (DCIS) who were selected on the basis of favorable clinical and pathologic ...
Sep 17, 2015
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