New model helps identify mutations that drive cancer
Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.
Jun 20, 2022
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Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.
Jun 20, 2022
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A team of researchers at the University of Michigan Rogel Cancer Center were the first to generate a bona fide mouse model of a Merkel cell carcinoma, a rare and potentially aggressive form of skin cancer. The study outlining ...
Jun 15, 2022
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Blood vessels are the body's essential architecture that exists in order to nurture cells with sufficient nutrients and oxygen. Angiogenesis, or the formation of new blood vessels, is of great research interest in cancer ...
Jun 13, 2022
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Nasopharyngeal carcinoma (NPC) is the most common malignant tumor of the head and neck in Southeast Asia and Southern China and originates from the epithelial tissue of the nasopharynx. Most NPCs are non-keratinizing cancers, ...
May 27, 2022
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Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.
May 20, 2022
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Nearly three decades after first discovering the tumor-suppressing Par-4 "super gene" that has been shown to kill cancer cells, a team of researchers at the University of Kentucky Markey Cancer Center is now learning about ...
May 16, 2022
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A new study published today in the journal Genes & Development reveals a gene that normally suppresses the formation of tumors but is reprogrammed at the onset of acute promyelocytic leukemia (APL), an aggressive type of ...
Apr 20, 2022
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Australian researchers have discovered a new neurodevelopmental disorder after uncovering its link to a tumor suppressor gene.
Apr 07, 2022
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A multidisciplinary team of researchers from Roswell Park Comprehensive Cancer Center and Kaiser Permanente Northern California have identified the first pharmacogenomic marker for anthracyclines and HER2-targeting drugs, ...
Mar 23, 2022
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A team of researchers from Massachusetts General Hospital (MGH) and Brigham and Women's Hospital (BWH) has reprogrammed the tumor microenvironment of liver cancer by using mRNA nanoparticles. This technology, similar to the ...
Feb 09, 2022
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A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes.
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