Researchers at Kanazawa University report in Cancer Research how Kras and p53 mutations influence the tumor suppressor and promoter functions of a TGF- ß pathway. The findings may lead to a new approach for colorectal cancer ...
Nov 29, 2023
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The p53 protein is a tumor suppressor that plays a crucial role in preventing the formation of cancerous cells. But when it mutates and becomes defective in cells, the protein can significantly boost a person's risk of cancer ...
Nov 28, 2023
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The strangely named hedgehog pathway that's crucial to bone growth has emerged as a key in the fight to treat the bone cancer osteosarcoma.
Nov 28, 2023
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A review paper titled "Targeting Ras with protein engineering" has been published in Oncotarget.
Nov 27, 2023
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Researchers led by Prof. Bu Pengcheng from the Institute of Biophysics of the Chinese Academy of Sciences and their collaborators have revealed that the CAR-like membrane protein (CLMP) is a tumor suppressor and determines ...
Nov 20, 2023
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Imagine the body's cells are well-behaved students in the classroom. The "teachers" are tumor suppressor genes, and they make sure cells follow the rules. But when tumor suppressor genes are away, cells may go astray.
Nov 1, 2023
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A new editorial paper titled "Neutrophil PAD4: how does it function in cancer beyond promoting NETosis?" has been published in Oncotarget.
Oct 30, 2023
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It has sparked numerous debates. Is there a connection between soy and breast cancer? Soy contains isoflavones, which are plant estrogens. High estrogen levels have been linked to an increased risk of breast cancer. However, ...
Oct 20, 2023
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The population of childhood cancer survivors in the U.S. is increasing, with an overall childhood cancer survival rate greater than 85% five years after diagnosis. However, survivors can still be at increased risk of various ...
Oct 2, 2023
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Northwestern Medicine investigators have discovered how the protein PD-1 controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas (T-NHLs), according to a study published ...
Sep 21, 2023
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A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes.
This text uses material from Wikipedia, licensed under CC BY-SA
