Results of a study led by VHIO investigators and published in Nature Medicine have unmasked mutations in the RNF43 gene as predictive biomarkers of response to treatment with anti-BRAF/EGFR combinatory therapy in patients ...
Sep 27, 2022
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A new study led by the Masonic Medical Research Institute published in the journal Cells shows for the first time that a particular gene, called VGLL4, is required for embryo development but is dispensable for myocardial ...
Sep 21, 2022
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The way that tumor cells enable their uncontrolled growth is also a weakness that can be harnessed to treat cancer, researchers at the University of Michigan and Indiana University have shown.
Sep 21, 2022
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In a May publication in iScience, researchers led by Ludwig Johns Hopkins's Ashley Cook, Nicolas Wyhs, Kenneth Kinzler and Shibin Zhou described their creation of a panel of isogenic—or genetically identical—cell lines ...
Sep 20, 2022
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Certain genetic variants found in prostate tumors of men of African descent were associated with African ancestry, according to two studies presented at the 15th AACR Conference on the Science of Cancer Health Disparities ...
Sep 19, 2022
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Cleveland Clinic researchers have uncovered genomic characteristics of breast cancers associated with PTEN hamartoma tumor syndrome (PHTS) that differentiate them from sporadic breast cancers. The findings, published in the ...
Aug 4, 2022
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Researchers at Vanderbilt University Medical Center have discovered a potential new target in the fight against colorectal cancer, the nation's third most common malignancy and, next to lung cancer, the second leading cancer ...
Jul 28, 2022
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Proteins that are frequently altered in tumors play a prominent role in cancer research. The protein RFX7, a largely unknown transcription factor, has recently been linked to lymph node cancer. Researchers at the Leibniz ...
Jul 19, 2022
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Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.
Jun 20, 2022
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A team of researchers at the University of Michigan Rogel Cancer Center were the first to generate a bona fide mouse model of a Merkel cell carcinoma, a rare and potentially aggressive form of skin cancer. The study outlining ...
Jun 15, 2022
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