Oncology & Cancer

Q&A: When will patients see personalized cancer vaccines?

Catherine Wu has been a pioneer in a promising approach to fight cancer: vaccines that target specific immune-stimulating molecules, known as immunogenic peptides, generated by the distinct genetic mutations of any individual ...

Oncology & Cancer

Improving cancer immunotherapy by prolonging T-cell survival

In the past decade, immunotherapy has emerged as the fourth pillar of cancer treatment, joining surgery, radiotherapy and chemotherapy. It is an approved treatment for 15 cancers, including melanoma and some types of lymphomas ...

Oncology & Cancer

New technique improves T cell-based immunotherapies for solid tumors

Scientists from Scripps Research have enhanced an existing immunotherapy by removing the sugar coating surrounding solid tumors—such as in melanoma, breast, and prostate cancer—so T cells can more effectively kill tumor ...

Oncology & Cancer

Potential therapeutic target for small cell lung cancer discovered

Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell lung cancer (SCLC) cells may decrease cancer cell differentiation and tumor ...

Oncology & Cancer

Novel mechanism supports antitumor response and T-cell survival

A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of ...

Immunology

Protein responsible for genetic inflammatory disease identified

A team of researchers led by Dr. Hirotsugu Oda at the University of Cologne's CECAD Cluster of Excellence for Aging Research has discovered the role a specific protein complex plays in certain forms of immune dysregulation. ...

Oncology & Cancer

Tumor deposits in colorectal and gastric cancers

Tumor deposits (TDs), initially recognized in colorectal cancer, have been identified in various other cancer types, including gastric cancer. It is defined as aggregates of tumor cells found in adipose and fibrous tissues ...

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