Immunology

Immune responses in chronic inflammatory bowel diseases

Chronic inflammatory bowel diseases (IBDs) like Crohn's disease and ulcerative colitis are characterized by inflammation of the gastrointestinal tract which flares up in phases and which is accompanied by abdominal pain, ...

Immunology

Deciphering gut microbiome 'chatter' to combat IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms. Crohn's Disease and Ulcerative ...

Biomedical technology

Customized cushions for wheelchairs could prevent pressure ulcers

Wheelchair users can periodically suffer from skin ulcers or sores caused by friction, pressure, and shear stresses where their skin is constantly in contact with the synthetic materials of their wheelchair. Pressure sores ...

Medical research

Infusion of 3D cellular structures might repair damaged intestine

Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis affects the innermost lining of the colon and rectum. It can be a debilitating ...

Immunology

Newly identified protein may help diagnose ulcerative colitis

An international research collaboration has discovered a potential new diagnostic marker for ulcerative colitis in a trans-ethnic analysis of Japanese and white patients. The finding could lead to the development of non-invasive, ...

Gastroenterology

Certain dietary patterns may raise risk for developing IBD

(HealthDay)—Dietary patterns are associated with the risk for developing inflammatory bowel disease (IBD), with an increased risk for Crohn disease (CD) seen in association with a Western dietary pattern and an increased ...

Inflammatory disorders

Inflammatory bowel disease: Incidence and treatment

Inflammatory bowel disease (IBD), with its two main disease entities Crohn's disease and ulcerative colitis, is a chronic and relapsing inflammation of the gastrointestinal tract. The highest prevalence of IBD is found in ...

Oncology & Cancer

Identification of a novel therapeutic target in multiple myeloma

Multiple myeloma is a cancer of the bone marrow, with a life expectancy of less than 5 years post-diagnosis. Proteasome inhibitors, the therapeutic backbone of current treatments, are very effective in treating newly diagnosed ...

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