Diseases, Conditions, Syndromes

The rocky road to a better flu vaccine

Currently approved flu vaccines are less effective in the elderly, yet an estimated 90% of influenza-related deaths occur in people over 65. A paper published on January 23rd in PLOS Pathogens reports on the challenges scientists ...

Diseases, Conditions, Syndromes

New discovery may lead the way to improved whooping cough vaccine

Scientists at Trinity College Dublin have made novel discoveries concerning the current vaccine against whooping cough that may lead to the development of an improved future vaccine. The findings could help reduce the incidence ...

Medical research

Vaccine adjuvant uses host DNA to boost pathogen recognition

Aluminum salts, or alum, have been injected into billions of people as an adjuvant to make vaccines more effective. No one knows, however, how they boost the immune response. In the March 19, 2013, issue of the Proceedings ...

Alzheimer's disease & dementia

Major step toward an Alzheimer's vaccine

A team of researchers from Université Laval, CHU de Québec, and pharmaceutical firm GlaxoSmithKline (GSK) has discovered a way to stimulate the brain's natural defense mechanisms in people with Alzheimer's disease. This ...

Immunology

Flu vaccine research: overcoming 'original sin'

(Medical Xpress) -- Scientists studying flu vaccines have identified ways to overcome an obstacle called "original antigenic sin," which can impair immune responses to new flu strains.

Medical research

Research describes advantages of new vaccine adjuvant

New research from the laboratory of Dr. Elizabeth Leadbetter at the Trudeau Institute may lead to a whole new class of vaccines. Dr. Leadbetter's lab has discovered new properties of a potential vaccine adjuvant that suggest ...

Diseases, Conditions, Syndromes

The H1N1 flu vaccine protects both pregnant women and newly-borns

The researchers studied the immune response of 107 pregnant women after they were injected with a single dose of non-adjuvant H1N1 vaccine. They concluded that the influenza shot boosted the immune response in pregnant women ...

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