Rare predicted loss-of-function (pLOF) variants and a polygenic risk score (PRS) are associated with increased atrial fibrillation (AF) risk, according to a study published online June 26 in JAMA Cardiology.
Jun 27, 2024
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As scorching summer temperatures drive Americans indoors and millions travel for vacations and family gatherings, COVID infections are again climbing, U.S. health officials warned Monday.
Jun 25, 2024
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The cumulative risk for advanced gastric cancer varies from 6.5 to 10.3% for carriers of germline CDH1 pathogenic/likely pathogenic (P/LP) variants, according to a study published online June 14 in the Journal of the American ...
Jun 21, 2024
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A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals—Mass Eye and Ear and ...
Jun 19, 2024
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It was earlier discovered that a variation in the PAX4 gene specifically predisposes East Asians to a higher risk of developing type 2 diabetes (T2D), increasing lifetime risk by up to 1.8 times. A new study, now published ...
Jun 14, 2024
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Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman's two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX. These genetic variants may ...
Jun 12, 2024
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Researchers from Japan have uncovered the genetic diversity and regional patterns of CARD9 deficiency in patients susceptible to fungal diseases.
Jun 11, 2024
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Bacteria, parasites, viruses—the immune system tackles them all. At the front line of the human immune response are cells called macrophages, which are responsible for correctly identifying intruders and then directing ...
Jun 5, 2024
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How exactly do SARS-CoV-2 particles enter host cells? An international team led by Dr. Richard Brown from Dr. Daniel Todt's Computational Virology group at the Department of Molecular and Medical Virology at Ruhr University ...
May 31, 2024
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A new proof-of-concept study by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) shows that changing only a single letter in the DNA code of selected genes in T cells may lead to improved cell therapy. ...
May 29, 2024
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