Diseases, Conditions, Syndromes

New look at atherosclerosis

Atherosclerosis is the slow and progressive narrowing of arteries due to plaque formation. The atherosclerotic plaque forms by local proliferation of leukocytes and vascular smooth muscle cells (VSMCs) in the vessel wall ...

Cardiology

Ca2+, the intercellular signal in arterioles

Vasoconstriction must be balanced with vasodilation, particularly in the arterioles that supply tissues with blood. Endothelial cells protrude through holes in the internal elastic lamina in arterioles to make contact with ...

Diabetes

Researchers implicate suspect in heart disease linked to diabetes

People with diabetes are at high risk of developing heart disease. Despite knowing this, scientists have struggled to trace the specific biology behind that risk or find ways to intervene. Now, UNC School of Medicine researchers ...

Diabetes

Study suggests route to improve artery repair

People with any form of diabetes are at greater risk of developing cardiovascular conditions than people without the disease. Moreover, if they undergo an operation to open up a clogged artery by inserting a "stent" surgical ...

Cardiology

New drug could help prevent artery disease in high-risk patients

According to the American Heart Association, approximately 2,200 Americans die each day from heart attacks, strokes and other cardiovascular diseases. The most common cause is blocked blood vessels that can no longer supply ...

Medical research

How mechanical stretching forces impact human vascular cells

Cardiovascular diseases are globally the main cause of death and vascular tissue integrity is important for the proper functionality and homeostasis of the blood system. Therefore, a profound understanding of vascular cell ...

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