A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, ...
Jun 2, 2022
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2
A correlation between a first dose of the AstraZeneca vaccine and a small but significant rise in cases of the serious neurological condition Guillain-Barré syndrome (GBS), has been identified by University College London ...
May 30, 2022
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419
A comparison of four COVID-19 vaccinations shows that messenger RNA (mRNA) vaccines from Pfizer-BioNTech and Moderna perform better against the World Health Organization's variants of concern (VOCs) than viral vector vaccines ...
May 17, 2022
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138
Delivered using adenovirus (Ad) vectors, therapeutic genes address the cause of disease—not just the symptoms. However, while advances in the understanding of human diseases and the genome have led to an increasing number ...
May 11, 2022
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17
The first three coronavirus vaccines earned Emergency Use Authorization more than a year ago. To date, no other vaccines have been put into use in the U.S—but that will soon change. More than 40 vaccines are undergoing ...
May 5, 2022
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119
A new approach from Penn Medicine researchers could cut the time it takes to alter patients' immune cells for infusion back into the body to find and attack cancer. The cell manufacturing process for this type of immunotherapy ...
Mar 29, 2022
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133
Dexamethasone, a glucocorticoid with anti-inflammatory and immunosuppressive effects, can transiently increase the expression of therapeutic genes delivered using adeno-associated virus (AAV) vectors. A new study, which showed ...
Feb 1, 2022
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0
A Western University team's novel approach to developing a COVID-19 vaccine shows promise in inducing a robust immune response, early data shows.
Dec 20, 2021
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41
European Union health authorities on Tuesday backed using a mix of COVID-19 vaccines, saying it could in some cases produce a better response than a single jab.
Dec 7, 2021
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1
An international team of scientists believe they may have found a molecular mechanism behind the extremely rare blood clots linked to adenovirus COVID-19 vaccines.
Dec 2, 2021
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