Medical research

Heart repair factor boosted by RNA-targeting compound

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such ...

Immunology

St18 is a negative regulator of VEGF

Pro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopolysaccharide (LPS) are known to activate NF-kB. NF-kB is a master regulator of inflammation and induces pro-inflammatory cytokines. Although ...

Medical research

Researchers identify 'hot spots' for developing lymphatic vessels

When an embryo develops, a wide variety of proteins and enzymes trigger a series of biochemical reactions. The development of the lymphatic vasculature is crucially dependent on one specific protein—the growth factor VEGF-C. ...

Medical research

Researchers successfully stop blood vessel, tumor growth in mice

Scientists at the National Institutes of Health and other institutions have devised a new strategy to stop tumors from developing the new blood vessels they need to grow. Once thought to be extremely promising for the treatment ...

Medical research

Scientists breach brain barriers to attack tumors

The brain is a sort of fortress, equipped with barriers designed to keep out dangerous pathogens. But protection comes at a cost: These barriers interfere with the immune system when faced with dire threats such glioblastoma, ...

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