An existing blood cancer drug has shown promise in killing "silent" HIV cells in animal models and human cells from people living with HIV—a significant pre-clinical discovery that could lead to a cure for the disease.
Aug 31, 2023
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Chemotherapy has been the most effective treatment to date for young and fit patients with chronic lymphocytic leukemia (CLL). The disease is the most common form of leukemia in the Western world, causing a substantial health ...
May 10, 2023
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The anti-cancer medicine venetoclax could improve the current therapy for estrogen receptor-positive (ER+) breast cancer—the most common form of breast cancer in Australia—according to preclinical studies led by Walter ...
May 7, 2020
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Relapsed/refractory acute myeloid leukemia (AML), a blood cancer, has an extremely poor prognosis because of resistance to anti-cancer drugs and frailty of the patient's organ functions. A type of anti-tumor immunotherapy ...
Jul 18, 2024
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Standard of care treatment for acute myeloid leukemia (AML) is safe and effective for adults over 80, according to a study published in Blood Neoplasia. For roughly a quarter of patients, this treatment can durably prolong ...
May 9, 2024
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New research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for leukemia, provides benefits for patients with multiple myeloma when used in combination with another ...
Mar 25, 2024
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A new research paper titled "ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells" has been published in Oncotarget.
Mar 25, 2024
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A new editorial paper titled "Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability" has been published in Oncotarget.
Jun 28, 2023
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First-line ibrutinib (Imbruvica) plus venetoclax (Venclexta) led to high response and survival rates in patients with chronic lymphocytic leukemia (CLL) whether or not their cancer harbored high-risk genetic features typically ...
Jun 7, 2023
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Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone. Venetoclax is a new targeted therapy option for the treatment of ...
Feb 23, 2023
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