Monkeypox virus can be shed into the surrounding environment by people who are infected, particularly in shed skin particles and in debris from monkeypox skin lesions and scabs. The virus is relatively hardy and under appropriate ...
Oct 13, 2022
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Viral DNA can be frequently detected in different clinical samples from monkeypox-infected patients, including saliva and semen, according to a new study led by the Barcelona Institute for Global Health (ISGlobal), a center ...
Jul 14, 2022
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A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, ...
Jun 2, 2022
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Instead of relying on the cell's repair mechanisms, the vaccinia virus MacGyvers a tool for DNA repair from one that it already uses to copy DNA, reports a team of researchers at the Medical University of South Carolina (MUSC) ...
May 17, 2022
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Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the ...
Dec 21, 2021
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How would you go about solving a puzzle if you didn't know what pieces to use, how many you would need, how it was supposed to look when you were done or what possible function it would serve?
Oct 18, 2021
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The molecular world is full of surprises, and none more stunning than those occurring among the infinitesimal proteins that drive the activities guarding against viral infections and cancer.
Currently available COVID-19 vaccines rely on mRNA strands to teach the human immune system to recognize the SARS-CoV-2 virus. Now, researchers reporting in PLOS Neglected Tropical Diseases have reported the successful development ...
May 27, 2021
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DNA viruses, such as herpesviruses and poxviruses, are among the most prolific and deadly viruses on Earth. Their ability to proliferate widely is due in large part to the way these viruses incubate in the body. Many DNA ...
Feb 18, 2021
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How does SARS-CoV-2 evade our immune defenses? It's a good question, actually. When SARS-CoV-2 defeats host defenses, we need to know how it does so, and conversely, when host defenses prevail, that also needs to be understood. ...
