Gene therapies aim to cure severe, barely treatable monogentic diseases caused by a defect in a single gene. Medical hopes are correspondingly high. Some gene therapies have already been approved in Europe—for example, ...
Aug 2, 2022
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Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15% in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine ...
Jul 21, 2022
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A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, ...
Jun 2, 2022
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The body's innate immune system, active from birth, is the first line of defense against viruses and other pathogens that cause disease. Using vaccination as an example, after receiving a vaccine, pain, redness, or swelling ...
May 25, 2022
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A newly discovered gene defect among people of Inuit ancestry in Greenland, Canada and Alaska will possibly lead to screening of all newborn Inuits as they will otherwise be at risk of dying from child vaccines or simple ...
Apr 26, 2022
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A research team led by Jae Jung, Ph.D., Director of Cleveland Clinic's Global Center for Pathogen & Human Health Research, has uncovered the critical role a viral gene, ORF8, plays in infection and disease outcomes of Severe ...
Apr 7, 2022
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Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus ...
Apr 1, 2022
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As Americans cross their fingers, hoping the pandemic stays behind them, scientists across the country remain focused on the novel coronavirus, intent on combating its next move.
Mar 28, 2022
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New research at the University of Chicago has found differences in immune pathway activation to influenza infection between individuals of European and African genetic ancestry. Many of the genes that were associated with ...
Nov 25, 2021
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Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic ...
Nov 8, 2021
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