Medical research

Discovery challenges the foundations of gene therapy

A new publication by scientists from Children's Medical Research Institute has challenged one of the foundations of the gene therapy field and will help to improve strategies for treating serious genetic disorders of the ...

Neuroscience

Getting gene therapy to the brain

A lone genetic mutation can cause a life-changing disorder with effects on multiple body systems. Lysosomal storage diseases, for example, of which there are dozens, arise due to single mutations that affect production of ...

HIV & AIDS

Researchers discover how HIV hides from treatment

Even after successful antiretroviral therapy, HIV can hide dormant in a tiny number of immune system cells for decades and re-emerge to threaten the life of its host. Now Yale University researchers have discovered a molecular ...

Oncology & Cancer

CAR macrophages go beyond T cells to fight solid tumors

Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors. Now researchers from the Perelman School of Medicine at the University of Pennsylvania ...

HIV & AIDS

Drinking weakens bones of people living with HIV: study

For people living with HIV, any level of alcohol consumption is associated with lower levels of a protein involved in bone formation, raising the risk of osteoporosis, according to a new study by researchers from the Boston ...

HIV & AIDS

Does timing matter for initiating HIV therapy in infants?

Starting HIV antiretroviral therapy (ART) within hours of birth has been hypothesized to have positive effects raising the possibility of remission in some children with HIV. To test the hypothesis, researchers at Columbia ...

HIV & AIDS

Nurses can help manage drug interactions in HIV/Hep C treatment

(HealthDay)—Drug interactions between antiretroviral therapy (ART) and direct-acting antivirals (DAAs) pose a clinical challenge in patients with HIV/hepatitis C virus (HCV) coinfection, according to an article published ...

Oncology & Cancer

Drug shows promise as immune therapy for cancer

A therapy developed by Yale researchers stimulates immune cells to shrink or kill tumors in mice, according to a new study published in the Journal of Experimental Medicine. The therapy is effective alone or in combination ...

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