(HealthDay)—AMPK activation by metformin is associated with inhibition of interstitial fibrosis and suppression of transforming growth factor β-1 (TGF-β1), according to a study published online May 13 in Diabetes.
May 24, 2016
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Researchers at Wihuri Research Institute and University of Helsinki, Finland, in collaboration with scientists from Vanderbilt and Groningen Universities used recombinant gene transfer technologies to discover a fine-tuning ...
Apr 12, 2016
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Brown adipose tissue (BAT), a major site for mammalian non-shivering thermogenesis, could be a target for prevention and treatment of human obesity. Transient receptor potential vanilloid 2 (TRPV2), a Ca2+-permeable cation ...
Mar 11, 2016
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New research on the blood lipid-lowering protein FGF21 shows how it redistributes fatty acids by two distinct mechanisms. The discovery could lead to improved pharmaceutical treatment for type 2 diabetes and other obesity-related ...
Feb 11, 2016
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Mild stress stimulates the activity and heat production by brown fat associated with raised cortisol, according to a study published today in Experimental Physiology.
Feb 9, 2016
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(HealthDay)—Imatinib (Gleevec) blocks CDK5-mediated peroxisome proliferator-activated receptor γ (PPARγ) phosphorylation as an antagonist ligand, improving insulin sensitivity and promoting browning of white adipose tissue, ...
Jan 13, 2016
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The body's ability to harness heat production by converting white fat cells, which store calories, into beige fat cells, which burn energy, could help fight obesity, according to researchers at Georgia State University.
Dec 16, 2015
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The fatter we are, the more our body appears to produce a protein that inhibits our ability to burn fat, suggests new research published in the journal Nature Communications. The findings may have implications for the treatment ...
Nov 24, 2015
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In the past few years, research on gut microbiota (that is, all microorganisms, mainly bacteria, inhabiting our gut) has started to unravel its tremendous role in our body, and how it symbiotically affects the functioning ...
Nov 16, 2015
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A new study in animals suggests that skipping meals sets off a series of metabolic miscues that can result in abdominal weight gain.
May 19, 2015
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