Researchers at the University of Sussex have identified how differences in the genetic sequence of the two main strains of the cancer-associated Epstein-Barr virus (EBV) can alter the way the virus behaves when it infects ...
Jul 18, 2019
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An immune system protein that usually protects the body from pathogens is abnormally produced in the brain during Parkinson's disease, scientists from Sanford Burnham Prebys report. The discovery, published in Free Radical ...
Jul 18, 2019
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Hematopoiesis is the process of forming blood cells, which occurs predominantly in the bone marrow. The bone marrow produces all types of blood cells: red blood cells, platelets, and white blood cells (leucocytes). One of ...
Jul 17, 2019
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Researchers from the University of Turku have discovered a new route that transports subcutaneously administered antibodies into lymph nodes in just a few seconds. The discovery enables targeted therapies for the immune system.
Jun 26, 2019
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Non-classical monocytes were long thought to play a purely surveillance role in the immune system. With the aid of a novel marker (PD-L1), Ludwig-Maximilians-Universitaet (LMU) researchers in Munich have now shown that they ...
Jun 21, 2019
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Research supported by the Accelerating Medicines Partnership (AMP) on Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) provides new insights into tissue damage for these autoimmune conditions. Findings include ...
Jun 19, 2019
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A research group from MedUni Vienna and CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences has discovered a new mechanism by which cells communicate in inflammatory processes. This involves endogenous ...
Jun 14, 2019
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The virus responsible for chickenpox and shingles employs a powerful strategy of immune evasion, inhibiting the ability of natural killer cells to destroy infected cells and produce molecules that help control viral infection, ...
Jun 13, 2019
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Most of us have heard of viruses such as measles and mumps—not to mention the more serious HIV and Ebola. But who has heard of Human Cytomegalovirus (HCMV)? I certainly hadn't until I started my Ph.D. back in 2001.
Jun 11, 2019
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Cancer-related inflammation impacts significantly on cancer development and progression. New research has observed in zebrafish, for the first time, that inflammatory cells use weak spots or micro-perforations in the extracellular ...
Jun 04, 2019
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White blood cells (WBCs), or leukocytes (also spelled "leucocytes"), are cells of the immune system defending the body against both infectious disease and foreign materials. Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a hematopoietic stem cell. Leukocytes are found throughout the body, including the blood and lymphatic system.
The number of leukocytes in the blood is often an indicator of disease. There are normally between 4×109 and 1.1×1010 white blood cells in a litre of blood, making up approximately 1% of blood in a healthy adult. An increase in the number of leukocytes over the upper limits is called leukocytosis, and in leukopenia, this number is much lower than the lower limit. The physical properties of leukocytes, such as volume, conductivity, and granularity, may change due to activation, the presence of immature cells, or the presence of malignant leukocytes in leukemia.
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