Idiopathic scoliosis (IS) is a complex genetic disorder that affects approximately 4 per cent of children worldwide, yet its underlying biological cause remains unknown.
Dec 13, 2018
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Scientists from the University of Sheffield have successfully created zebrafish that carry the complex genetic change known to cause the most common genetic form of motor neurone disease (MND).
Nov 26, 2018
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Advances in optimisation of the gene-editing technique CRISPR/Cas9 in zebrafish disease models offer a new level of accuracy and specificity previously out of reach for research into human genetic disorders.
Oct 18, 2018
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By using a larval zebrafish model, Dr. Du Jiulin's lab at the the Institute of Neuroscience and Zunyi Medical College revealed that two commonly used intravenous anesthetic drugs, propofol and etomidate, suppress the excitability ...
Sep 20, 2018
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A popular aquarium fish may hold answers to how tumors form in a childhood cancer.
Jun 5, 2018
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As the opioid crisis escalates, the science behind addiction remains poorly understood. To address this need, researchers at University of Utah Health devised a system that allowed zebrafish, a small tropical fish, to self-administer ...
Aug 25, 2017
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Macquarie University researchers have developed the first zebrafish model of the neurodegenerative Machado-Joseph Disease – and have used this model to test drugs that could potentially be used to treat the disease, which ...
Aug 11, 2017
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The common zebrafish is a useful proxy for testing whether drug candidates cause organ damage. Now, researchers in Singapore have created two modified types of the fish, one that glows when experiencing toxicity, and another ...
Jul 26, 2017
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Pioneering research using the tropical zebrafish could provide new insights into the genetic basis of myopathy, a type of human muscle disease.
Jul 5, 2017
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"Bench-to-bedside" describes research that has progressed from basic science in animal models that has led to therapies used in patients. Now, a study in the journal Brain describes what could be considered a direct "aquarium-to-bedside" ...
Feb 10, 2017
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