African Sleeping Sickness
Drug treatment corrects autism symptoms in mouse model
Autism results from abnormal cell communication. Testing a new theory, researchers at the University of California, San Diego School of Medicine have used a newly discovered function of an old drug to restore cell communications ...
Autism spectrum disorders
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Diseases, Conditions, Syndromes
Feb 26, 2013 |
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Tuberculosis and neglected diseases targeted by new center
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Sleeping sickness by stealth
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Feb 05, 2013 |
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Wild animals may contribute to the resurgence of African sleeping sickness
Wild animals may be a key contributor to the continuing spread of African sleeping sickness, new research published in PLOS Computational Biology shows. The West African form of the disease, also known as Gambiense Human ...
Diseases, Conditions, Syndromes
Jan 17, 2013 |
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New oral drug candidate for African sleeping sickness
A new oral-only treatment for sleeping sickness has entered Phase II/III clinical study in patients with late-stage sleeping sickness in the Democratic Republic of the Congo (DRC) and soon in Central African Republic (CAR). ...
Medications
Dec 06, 2012 |
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Gene clue to drug resistance in African sleeping sickness
(Medical Xpress) -- Researchers have identified a gene that controls susceptibility to drug treatment in Trypanosoma brucei, the parasite responsible for African sleeping sickness.
Diseases, Conditions, Syndromes
Jun 19, 2012 |
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Old drug shows new promise to treat leishmaniasis
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Feb 02, 2012 |
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African sleeping sickness: a tale of two parasites
(Medical Xpress) -- The savannahs and rainforests of Africa bring to mind romantic notions of wildlife, adventure and exploration. But beneath this natural beauty lies a deadly, long-neglected disease: trypanosomiasis, ...
Diseases, Conditions, Syndromes
Dec 08, 2011 |
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Gene variant increases risk of kidney disease in African-Americans
African-Americans with two copies of the APOL1 gene have about a 4 percent lifetime risk of developing a form of kidney disease, according to scientists at the National Institutes of Health. The finding brings scientists ...
Diseases, Conditions, Syndromes
Oct 24, 2011 |
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Sleeping sickness drug may provide long-term protection against skin cancer
An antiparasitic agent used to treat African sleeping sickness might someday be used to prevent nonmelanoma skin cancers. Researchers found that DFMO, or α-difluoromethylornithine, still appeared to protect against nonmelanoma ...
Cancer
Oct 24, 2011 |
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First field-based molecular diagnostic test for African sleeping sickness in sight
The Geneva-based not-for-profit foundation FIND and Japanese diagnostics company Eiken announced today that a next-generation molecular test designed specifically for sleeping sickness – a deadly parasitic disease also ...
Diseases, Conditions, Syndromes
Sep 15, 2011 |
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UT Southwestern research team's anti-malarial work wins international Project of the Year award
The discovery of a potential new anti-malarial drug by a UT Southwestern Medical Center-led research team has been awarded Project of the Year by Medicines for Malaria Venture (MMV).
Diseases, Conditions, Syndromes
Jun 07, 2011 |
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Human African trypanosomiasis, sleeping sickness, African lethargy, or Congo trypanosomiasis is a parasitic disease of people and animals, caused by protozoa of the species Trypanosoma brucei and transmitted by the tsetse fly. The disease is endemic in some regions of sub-Saharan Africa, covering about 37 countries and 60 million people. It is estimated that 50,000 to 70,000 people are currently infected, the number having declined somewhat in recent years. The number of reported cases was below 10,000 in 2009, the first time in 50 years. It is believed that many cases go unreported. About 48,000 people died of it in 2008. Four major epidemics have occurred in recent history: one from 1896–1906 primarily in Uganda and the Congo Basin, two epidemics in 1920 and 1970 in several African countries, and a recent 2008 epidemic in Uganda.
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