In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, ...
May 26, 2017
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(Medical Xpress) -- The savannahs and rainforests of Africa bring to mind romantic notions of wildlife, adventure and exploration. But beneath this natural beauty lies a deadly, long-neglected disease: trypanosomiasis, otherwise ...
Dec 8, 2011
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In early drug discovery, you need a starting point, says Northeastern University associate professor of chemistry and chemical biology Michael Pollastri.
Oct 24, 2014
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Researchers at the Francis Crick Institute and University of Dundee have screened thousands of drug and chemical molecules and identified a range of potential antivirals that could be developed into new treatments for COVID-19 ...
Jul 2, 2021
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Researchers have turned a fungus into a disease-curing factory through modern genetic engineering and patience. The natural antibiotic is a promising cure for a neglected tropical disease called human African trypanosomiasis, ...
Apr 4, 2019
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Type 1 diabetes is an autoimmune disease that causes the body's immune system to attack and destroy insulin-producing beta cells in the pancreas. Traditional management of type 1 diabetes has primarily involved replacing ...
Nov 2, 2023
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Sixty million people in sub-Saharan Africa live at risk of African sleeping sickness, a disease caused by parasites transmitted through the tsetse fly. In the late stage of the disease, when the parasite crosses the blood-brain ...
Jul 5, 2018
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Scientists have made an important new discovery in the study of Human African Trypanosomiasis, more commonly known as African sleeping sickness. The findings could have a major impact on the way the disease is diagnosed, ...
Sep 23, 2016
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Some infectious diseases are particularly difficult to treat because of their ability to evade the immune system. One such illness, African sleeping sickness, is caused by the parasite Trypanosoma brucei, transmitted by the ...
Dec 8, 2015
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Six University of Aberdeen students will head to Boston on Wednesday to a major international science competition to showcase a new diagnostic tool they have created.
Oct 27, 2014
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Human African trypanosomiasis, sleeping sickness, African lethargy, or Congo trypanosomiasis is a parasitic disease of people and animals, caused by protozoa of the species Trypanosoma brucei and transmitted by the tsetse fly. The disease is endemic in some regions of sub-Saharan Africa, covering about 37 countries and 60 million people. It is estimated that 50,000 to 70,000 people are currently infected, the number having declined somewhat in recent years. The number of reported cases was below 10,000 in 2009, the first time in 50 years. It is believed that many cases go unreported. About 48,000 people died of it in 2008. Four major epidemics have occurred in recent history: one from 1896–1906 primarily in Uganda and the Congo Basin, two epidemics in 1920 and 1970 in several African countries, and a recent 2008 epidemic in Uganda.
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