Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis (ALS), a ...
Neuroscience Mar 31, 2013 | 5 / 5 (4) | 0 |
(HealthDay)—Researchers are testing whether applying electrical stimulation directly to the brains of people with Alzheimer's disease might improve thinking, focus and alertness.
Alzheimer's disease & dementia Mar 28, 2013 | 5 / 5 (3) | 0 |
Women who abruptly and prematurely lose estrogen from surgical menopause have a two-fold increase in cognitive decline and dementia.
Neuroscience Mar 28, 2013 | 3 / 5 (1) | 0
(Medical Xpress)—Researchers have shown they can predict impending cognitive decline using a sensitive behavioral task up to three years in advance of clinical evidence. Until now, it has not been possible to reliably differentiate ...
Alzheimer's disease & dementia Mar 27, 2013 | not rated yet | 0
Long term treatment by carmustine, a chemical relative of mustard gas and already used to treat some types of brain cancer, can decrease the amount of amyloid β and number of amyloid plaques in a mouse model of Alzheimer's ...
Alzheimer's disease & dementia Mar 25, 2013 | 5 / 5 (1) | 0
President John F. Kennedy's mission in 1960 was to land a man on the moon. President Bill Clinton made cracking the human genome one of his top priorities. Now, President Barack Obama says a detailed map ...
Neuroscience Mar 25, 2013 | 5 / 5 (4) | 0
Scientists at the Gladstone Institutes have discovered that a certain type of DNA damage long thought to be particularly detrimental to brain cells can actually be part of a regular, non-harmful process. The team further ...
Alzheimer's disease & dementia Mar 24, 2013 | 5 / 5 (7) | 1 |
The strongest predictor of whether a man is developing dementia with Lewy bodies—the second most common form of dementia in the elderly—is whether he acts out his dreams while sleeping, Mayo Clinic researchers have discovered. ...
Neuroscience Mar 21, 2013 | 5 / 5 (2) | 0
Researchers at The Scripps Research Institute (TSRI) in Jupiter, FL, have developed cutting-edge technology that can successfully screen human blood for disease markers. This tool may hold the key to better diagnosing and ...
Medical research Mar 21, 2013 | 5 / 5 (1) | 0 |
The neuroscience of finding your lost keys: How the brain keeps track of similar but distinct memories
Ever find yourself racking your brain on a Monday morning to remember where you put your car keys? When you do find those keys, you can thank the hippocampus, a brain region responsible for storing and retrieving ...
Neuroscience Mar 21, 2013 | 4 / 5 (1) | 0 |
(AP)—A northern Utah sheriff's office is floating a unique and unproven idea for keeping seniors with Alzheimer's disease and dementia safe: Give them ankle monitors normally used on criminals on house arrest or parole.
Alzheimer's disease & dementia Mar 20, 2013 | not rated yet | 0
Researchers at Georgetown University Medical Center (GUMC) have found what they say is evidence that veterans who suffer from "Gulf War Illness" have physical changes in their brains not seen in unaffected individuals. Brain ...
Neuroscience Mar 20, 2013 | 5 / 5 (1) | 0
New research from Wake Forest Baptist Medical Center is giving radiation oncologists who treat brain tumors a better understanding of how to preserve the brain's functions while still killing cancer.
Cancer Mar 20, 2013 | 4 / 5 (2) | 0
The Journal of Neuroscience has published a study led by researchers at the Max Planck Florida Institute for Neuroscience, the first and only U.S. extension of the prestigious Max Planck Society, that may hold a stunning breakt ...
Alzheimer's disease & dementia Mar 19, 2013 | 4.9 / 5 (7) | 2
Findings from a Loyola University Chicago Stritch School of Medicine study could lead to the development of new drugs to treat gout. The study, led by Liang Qiao, MD, and his colleagues and collaborators, was published March ...
Immunology Mar 19, 2013 | 5 / 5 (2) | 0 |
Alzheimer's disease (AD), also known in medical literature as Alzheimer disease, is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death. It was first described by German psychiatrist and neuropathologist Alois Alzheimer in 1906 and was named after him.
Most often, AD is diagnosed in people over 65 years of age, although the less-prevalent early-onset Alzheimer's can occur much earlier. In 2006, there were 26.6 million sufferers worldwide. Alzheimer's is predicted to affect 1 in 85 people globally by 2050.
Although Alzheimer's disease develops differently for every individual, there are many common symptoms. Early symptoms are often mistakenly thought to be 'age-related' concerns, or manifestations of stress. In the early stages, the most common symptom is difficulty in remembering recent events. When AD is suspected, the diagnosis is usually confirmed with tests that evaluate behaviour and thinking abilities, often followed by a brain scan if available.
As the disease advances, symptoms can include confusion, irritability and aggression, mood swings, trouble with language, and long-term memory loss. As the sufferer declines they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Since the disease is different for each individual, predicting how it will affect the person is difficult. AD develops for an unknown and variable amount of time before becoming fully apparent, and it can progress undiagnosed for years. On average, the life expectancy following diagnosis is approximately seven years. Fewer than three percent of individuals live more than fourteen years after diagnosis.
The cause and progression of Alzheimer's disease are not well understood. Research indicates that the disease is associated with plaques and tangles in the brain. Current treatments only help with the symptoms of the disease. There are no available treatments that stop or reverse the progression of the disease. As of 2012[update], more than 1000 clinical trials have been or are being conducted to find ways to treat the disease, but it is unknown if any of the tested treatments will work. Mental stimulation, exercise, and a balanced diet have been suggested as possible ways to delay symptoms in healthy older individuals, but they have not been proven as effective.
Because AD cannot be cured and is degenerative, the sufferer relies on others for assistance. The role of the main caregiver is often taken by the spouse or a close relative. Alzheimer's disease is known for placing a great burden on caregivers; the pressures can be wide-ranging, involving social, psychological, physical, and economic elements of the caregiver's life. In developed countries, AD is one of the most costly diseases to society.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
Latest Spotlight News
In a remote fishing community in Venezuela, a lone fisherman sits on a cliff overlooking the southern Caribbean Sea. This man –– the lookout –– is responsible for directing his comrades on the water, ...
38 minutes ago | not rated yet | 0 |
(HealthDay)—Obese and overweight men and women who suffer from heartburn often report relief when they lose weight, a new study shows.
2 hours ago | not rated yet | 0 |
(HealthDay)—Injections of a sugar solution appear to help relieve knee pain and stiffness related to osteoarthritis, a new study suggests.
2 hours ago | 4 / 5 (1) | 0 |
Over the past few decades, scientists have developed many devices that can reopen clogged arteries, including angioplasty balloons and metallic stents. While generally effective, each of these treatments ...
2 hours ago | 5 / 5 (1) | 0 |
Johns Hopkins researchers say they have discovered specific chemical alterations in two genes that, when present during pregnancy, reliably predict whether a woman will develop postpartum depression.
5 hours ago | not rated yet | 0 |
(Medical Xpress)—Scientists at the School of Medicine have shown that their previously identified therapeutic approach to fight cancer via immune cells called macrophages also prompts the disease-fighting killer T cells ...
2 hours ago | not rated yet | 0 |
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
15 hours ago | 4.6 / 5 (14) | 7 |
(Medical Xpress)—Cardiologists have identified a trio of biomarkers that may predict which patients with heart disease have a high risk of heart attack or death in the next two years.
3 hours ago | not rated yet | 0 |
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
18 hours ago | 4.8 / 5 (13) | 3 |
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
18 hours ago | 4.9 / 5 (7) | 4 |