Cardiology

Medications for enlarged prostate linked to heart failure risk

Widely used medications for benign prostatic hyperplasia (BPH)—also known as enlarged prostate—may be associated with a small, but significant increase in the probability of developing heart failure, suggests a study ...

Diseases, Conditions, Syndromes

Noninvasive treatment for men suffering from enlarged prostate

Physicians from Sapienza University in Rome have published promising results of a small prospective interventional trial using noninvasive pulsed electromagnetic field therapy (PEMF) to treat men suffering from benign prostatic ...

Diseases, Conditions, Syndromes

Nonsurgical treatment for enlarged prostate on the horizon

You just cannot ignore your symptoms any longer. You find yourself getting up many times every night with the urgency to urinate. Saw palmetto, even high doses of the highest-quality type, didn't work.

Oncology & Cancer

New prostate cancer test more specific, sensitive than PSA test

A new test for prostate cancer that measures levels of prostate specific antigen (PSA) as well as six specific antibodies found in the blood of men with the disease was more sensitive and more specific than the conventional ...

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Benign prostatic hyperplasia (BPH) also known as benign prostatic hypertrophy (technically a misnomer), benign enlargement of the prostate (BEP), and adenofibromyomatous hyperplasia, refers to the increase in size of the prostate.

Properly, BPH involves hyperplasia rather than hypertrophy, but the nomenclature is often interchangeable, even amongst urologists. It involves hyperplasia of prostatic stromal and epithelial cells, resulting in the formation of large, fairly discrete nodules in the periurethral region of the prostate. When sufficiently large, the nodules compress the urethral canal to cause partial, or sometimes virtually complete, obstruction of the urethra, which interferes with the normal flow of urine. It leads to symptoms of urinary hesitancy, frequent urination, dysuria (painful urination), increased risk of urinary tract infections, and urinary retention. Although prostate specific antigen levels may be elevated in these patients because of increased organ volume and inflammation due to urinary tract infections, BPH is not considered to be a premalignant lesion.

Adenomatous prostatic growth is believed to begin at approximately age 30 years. An estimated 50% of men have histologic evidence of BPH by age 50 years and 75% by age 80 years. In 40-50% of these patients, BPH becomes clinically significant.

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