Childhood Cancer

Delays in diagnosis worsen outlook for minority, uninsured pediatric retinoblastoma patients

When the eye cancer retinoblastoma is diagnosed in racial and ethnic minority children whose families don't have private health insurance, it often takes a more invasive, potentially life-threatening course than in other ...

Cancer created Apr 24, 2013 | popularity not rated yet | comments 1

Genetic biomarker may help identify neuroblastomas vulnerable to novel class of drugs

An irregularity within many neuroblastoma cells may indicate whether a neuroblastoma tumor, a difficult-to-treat, early childhood cancer, is vulnerable to a new class of anti-cancer drugs known as BET bromodomain inhibitors, ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Study finds potential link between auto pollution, some childhood cancers

Scientists from UCLA's Fielding School of Public Health led by Julia Heck, an assistant researcher in the school's epidemiology department and a member of UCLA's Jonsson Comprehensive Cancer Center, have found a possible ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

New genetic link found between normal fetal growth and cancer

Two researchers at the National Institutes of Health discovered a new genetic link between the rapid growth of healthy fetuses and the uncontrolled cell division in cancer. The findings shed light on normal development and ...

Genetics created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Immunotherapy showed promising antileukemia activity in pediatric patients

Researchers using patients' own immune cells in an immunotherapy approach called "anti-CD19 chimeric antigen receptor (CAR) T-cell therapy," achieved responses in children whose acute lymphocytic leukemia (ALL) had returned ...

Cancer created Apr 07, 2013 | popularity 5 / 5 (1) | comments 0

Researchers to develop next generation immunotherapy for children with deadly solid tumors

Recently, research using adoptive T-cell immunotherapy in blood cancers have shown success, most notably in the case of a seven-year-old girl whose leukemia went into remission using altered T-cells and a disabled HIV virus. ...

Cancer created Apr 03, 2013 | popularity 5 / 5 (1) | comments 0

T-cell therapy eradicates an aggressive leukemia in two children

Two children with an aggressive form of childhood leukemia had a complete remission of their disease-showing no evidence of cancer cells in their bodies-after treatment with a novel cell therapy that reprogrammed their immune ...

Cancer created Mar 25, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Inherited genetic variations have a major impact on childhood leukemia risk

Humans have between 20,000 and 25,000 genes that carry instructions for assembling the proteins that do the work of cells. Work led by St. Jude Children's Research Hospital found that children who inherit certain variations ...

Cancer created Mar 19, 2013 | popularity not rated yet | comments 0 | with audio podcast

Sorting out fertility after childhood cancer

As success rates in treating childhood cancers have improved, greater emphasis is being placed on quality of life issues following successful treatment. Many cancer treatments can lead to infertility, but there are few methods ...

Cancer created Mar 15, 2013 | popularity 5 / 5 (1) | comments 0

Breakthrough in battle against leukemia

Scientists at Griffith University's Institute for Glycomics and The Saban Research Institute of Children's Hospital Los Angeles have discovered a critical weakness in leukaemic cells, which may pave the way to new treatments.

Cancer created Mar 13, 2013 | popularity 5 / 5 (5) | comments 0

FSH, inhibin B poor predictors of sperm count after cancer

(HealthDay)—Serum levels of follicle-stimulating hormone (FSH) and inhibin B are not good predictors of sperm levels in male survivors of childhood cancer, according to a study published online Feb. 19 ...

Cancer created Mar 08, 2013 | popularity 5 / 5 (1) | comments 0

Biomarker may identify neuroblastomas with sensitivity to BET bromodomain inhibitors

Neuroblastoma, the most common malignant tumor of early childhood, is frequently associated with the presence of MYCN amplification, a genetic biomarker associated with poor prognosis. Researchers have determined that tumors ...

Cancer created Feb 21, 2013 | popularity not rated yet | comments 0

Childhood cancer in developing countries—a growing health threat that could be easily managed

Across the developing world, childhood cancer is on the rise, and mortality is high. Once thought of as a rich world disease, cancer is a growing health threat across low-income and middle-income countries (LMCs). A major ...

Cancer created Feb 19, 2013 | popularity not rated yet | comments 0

Improvement in child cancer survival rates threatened by lack of new drug development

Remarkable improvements in survival from childhood cancer have taken place in high- income countries over the past 50 years, but further progress is being threatened by increasingly strict research regulations and insufficient ...

Cancer created Feb 19, 2013 | popularity not rated yet | comments 0

Study finds mutations linked to relapse of childhood leukemia

After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...

Genetics created Feb 03, 2013 | popularity not rated yet | comments 0 | with audio podcast


The Childhood Cancer Research Group' (CCRG) is part of the University Department of Paediatrics at the University of Oxford, England. The CCRG maintains the National Registry of Childhood Tumours (NRCT), which is said to be the largest childhood cancer registry in the world.

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