Cancer biologists are yet to understand the mechanisms and cellular hierarchy leading to the developmental arrest in rhabdomyosarcoma (RMS)—a group of pediatric cancers, which remain enigmatic.
Doctors who treat children with the most common form of childhood cancer – acute lymphoblastic leukemia – are often baffled at how sometimes the cancer cells survive their best efforts and the most powerful modern ...
May 18, 2011
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Researchers have identified new variations in neuroblastoma that could lead to a more accurate prognosis and better-targeted treatments for this devastating childhood cancer.
Apr 9, 2024
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Follow-up and treatment of children with cancer is significantly improved when inherited genetic causes are also investigated, according to a new Swedish study. The results of the research involving some 50 researchers and ...
Apr 2, 2024
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The MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it difficult to treat various human cancers. When MYCN is overactive, especially in high-risk neuroblastoma ...
Mar 15, 2024
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Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer ...
Mar 7, 2024
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Three out of four children with cancer are successfully treated and survive the disease. But the treatment, which often consists of a combination of surgery, chemotherapy and radiation, can cause serious side effects and ...
Sep 11, 2023
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Scientists at St. Jude Children's Research Hospital comprehensively characterized oncogenic fusions in pediatric cancer, providing proof-of-principle for genetic engineering-based therapies.
Apr 5, 2023
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Improving the seasonal influenza vaccine and public health specialists' ability to predict pandemic potential in new flu strains may be possible, due to new findings from scientists at St. Jude Children's Research Hospital. ...
Mar 29, 2023
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Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults. The finding has implications ...
Oct 12, 2022
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The Childhood Cancer Research Group' (CCRG) is part of the University Department of Paediatrics at the University of Oxford, England. The CCRG maintains the National Registry of Childhood Tumours (NRCT), which is said to be the largest childhood cancer registry in the world.
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