Childhood Cancer

Common anti-inflammatory coaxes liver cancer cells to commit suicide

The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.

Cancer created May 16, 2011 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

World's largest release of comprehensive human cancer genome data helps speed discoveries

To speed progress against cancer and other diseases, the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project today announced the largest-ever release of comprehensive human cancer ...

Genetics created May 29, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Breakthrough in battle against leukemia

Scientists at Griffith University's Institute for Glycomics and The Saban Research Institute of Children's Hospital Los Angeles have discovered a critical weakness in leukaemic cells, which may pave the way to new treatments.

Cancer created Mar 13, 2013 | popularity 5 / 5 (5) | comments 0

Investigational agent shows promise in reducing spread of prostate cancer

A drug developed to treat Ewing's Sarcoma, a rare childhood cancer, may also help prevent human prostate cancer from spreading, as seen in new lab studies say researchers at Georgetown Lombardi Comprehensive Cancer Center, ...

Cancer created Apr 29, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

T-cell therapy eradicates an aggressive leukemia in two children

Two children with an aggressive form of childhood leukemia had a complete remission of their disease-showing no evidence of cancer cells in their bodies-after treatment with a novel cell therapy that reprogrammed their immune ...

Cancer created Mar 25, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Key to fighting drug-resistant leukemia found

Doctors who treat children with the most common form of childhood cancer – acute lymphoblastic leukemia – are often baffled at how sometimes the cancer cells survive their best efforts and the most powerful modern ...

Cancer created May 18, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Childhood leukaemia study points to smoking fathers

Research from Western Australia’s Telethon Institute for Child Health Research finds that heavy smoking by fathers around the time of conception greatly increases the risk of the child developing Acute ...

Health created Feb 09, 2012 | popularity 5 / 5 (3) | comments 0

US cancer death rates continue to decline, national report finds

A report from the nation's leading cancer organizations shows rates of death in the United States from all cancers for men and women continued to decline between 2000 and 2009. The findings come from the latest Annual Report ...

Cancer created Jan 08, 2013 | popularity 4.3 / 5 (3) | comments 1

Researchers develop first 'theranostic' treatment for acute lymphoblastic leukemia (ALL)

A team of researchers at Case Western Reserve University School of Medicine has developed the first "theranostic" agent for the treatment of acute lymphoblastic leukemia (ALL). ALL is the most common type of childhood cancer ...

Cancer created Mar 07, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Leukemia patients remain in remission more than two years after engineered T cell therapy

Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients' tumors responded to the therapy, which was pioneered by scientists in the ...

Cancer created Dec 10, 2012 | popularity 5 / 5 (2) | comments 0

Tumors evolve rapidly in a childhood cancer, leaving fewer obvious tumor targets

An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene ...

Genetics created Jan 20, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Sleep issues contribute to cognitive problems in childhood cancer survivors

A new analysis has found that childhood cancer survivors often suffer from sleep problems and fatigue, which negatively impact their attention and memory. Published early online in Cancer, a peer-reviewed journal of the Am ...

Cancer created Apr 11, 2011 | popularity 5 / 5 (1) | comments 0

Antibody-guided drug works against acute lymphoblastic leukemia

An antibody packaged with a potent chemotherapy drug to selectively destroy acute lymphoblastic leukemia (ALL) cells eradicated or greatly reduced the disease for 61 percent of 46 patients in a phase II study. It will be ...

Cancer created May 23, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Childhood cancer survivors at greater risk in middle age

Scientists at the University of Birmingham have found that survivors of childhood cancers are four times more likely than the general population to develop a new cancer. The results are published online today in the Journal of ...

Cancer created Jun 06, 2011 | popularity 5 / 5 (1) | comments 0

Mutations in essential genes often cause rare diseases

Mutations in genes essential to survival are behind so-called orphan diseases, explaining in part why these diseases are rare and often deadly, according to a study appearing in The American Journal of Human Genetics.

Genetics created Jun 09, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast


The Childhood Cancer Research Group' (CCRG) is part of the University Department of Paediatrics at the University of Oxford, England. The CCRG maintains the National Registry of Childhood Tumours (NRCT), which is said to be the largest childhood cancer registry in the world.

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Latest Spotlight News

Researchers find common childhood asthma unconnected to allergens or inflammation

Little is known about why asthma develops, how it constricts the airway or why response to treatments varies between patients. Now, a team of researchers at Weill Cornell Medical College, Columbia University Medical Center ...

Scientists discover molecule triggers sensation of itch

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Multiple research teams unable to confirm high-profile Alzheimer's study

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Drug reverses Alzheimer's disease deficits in mice, research confirms

An anti-cancer drug reverses memory deficits in an Alzheimer's disease mouse model, University of Pittsburgh Graduate School of Public Health researchers confirm in the journal Science.

Antibiotics: A new understanding of sulfonamide nervous system side effects

Since the discovery of Prontosil in 1932, sulfonamide antibiotics have been used to combat a wide spectrum of bacterial infections, from acne to chlamydia and pneumonia. However, their side effects can include serious neurological ...

Economic incentives increase blood donation without negative consequences

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Motion quotient: IQ predicted by ability to filter motion (w/ video)

A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...

The secret lives, and deaths, of neurons

As the human body fine-tunes its neurological wiring, nerve cells often must fix a faulty connection by amputating an axon—the "business end" of the neuron that sends electrical impulses to tissues or other ...

Protein preps cells to survive stress of cancer growth and chemotherapy

Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumors.