Chronic Alcoholism

Heavy drinking rewires brain, increasing susceptibility to anxiety problems

Doctors have long recognized a link between alcoholism and anxiety disorders such as post-traumatic stress disorder (PTSD). Those who drink heavily are at increased risk for traumatic events like car accidents and domestic ...

Neuroscience created Sep 02, 2012 | popularity 4.5 / 5 (4) | comments 2 | with audio podcast

Liver mitochondria improve, increase after chronic alcohol feeding in mice

(Medical Xpress)—Scientists at the Keck School of Medicine of the University of Southern California (USC) have found evidence that liver mitochondria in mice adapt to become better metabolizers of alcohol and increase in ...

Medical research created Dec 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Chronic alcohol and marijuana use during youth can compromise white-matter integrity

Chronic use of alcohol and marijuana during youth is associated with poorer neural structure, function, and metabolism, as well as worsened neurocognitive abilities into later adolescence and adulthood. This may be due to ...

Addiction created Dec 14, 2012 | popularity not rated yet | comments 6 | with audio podcast

Researchers uncover gender differences in the effects of long-term alcoholism

Researchers from Boston University School of Medicine (BUSM) and Veterans Affairs (VA) Boston Healthcare System have demonstrated that the effects on white matter brain volume from long-term alcohol abuse are different for ...

Addiction created Aug 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Wiping memories to tackle alcoholism

(Medical Xpress) -- Researchers at the University of Cambridge believe connections developed in the brain between the ‘drug high’ of alcohol and the situations in which it’s used create loaded ...

Psychology & Psychiatry created Mar 13, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Math can save Tylenol overdose patients

University of Utah mathematicians developed a set of calculus equations to make it easier for doctors to save Tylenol overdose patients by quickly estimating how much painkiller they took, when they consumed ...

Medical research created Feb 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

Drinking alcohol shrinks critical brain regions in genetically vulnerable mice

Brain scans of two strains of mice imbibing significant quantities of alcohol reveal serious shrinkage in some brain regions - but only in mice lacking a particular type of receptor for dopamine, the brain's "reward" chemical. ...

Medical research created Feb 15, 2012 | popularity not rated yet | comments 0 | with audio podcast

Alcohol impairs the body's ability to fight off viral infection

Alcohol is known to worsen the effects of disease, resulting in longer recovery period after trauma, injury or burns. It is also known to impair the anti-viral immune response, especially in the liver, including response ...

Health created Sep 30, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists find key mechanism in transition to alcohol dependence

A team of Scripps Research Institute scientists has found a key biological mechanism underpinning the transition to alcohol dependence. This finding opens the door to the development of drugs to manage excessive alcohol consumption.

Psychology & Psychiatry created May 31, 2011 | popularity not rated yet | comments 0 | with audio podcast

Antioxidant may prevent alcohol-induced liver disease

An antioxidant may prevent damage to the liver caused by excessive alcohol, according to new research from the University of Alabama at Birmingham. The findings, published online April 21, 2011, in the journal Hepatology, may po ...

Diseases, Conditions, Syndromes created May 02, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New research shows weekend binge drinking could leave lasting liver damage

Long after a hangover, a night of bad decisions might take a bigger toll on the body than previously understood. Described in the current issue of Alcoholism: Clinical & Experimental Research, a study at the University of Missouri has revealed a ...

Health created May 01, 2013 | popularity not rated yet | comments 0

Researchers find that alcohol consumption damages brain's support cells

Alcohol consumption affects the brain in multiple ways, ranging from acute changes in behavior to permanent molecular and functional alterations. The general consensus is that in the brain, alcohol targets mainly neurons. ...

Neuroscience created Mar 18, 2013 | popularity 3 / 5 (1) | comments 0

First guidelines for brain amyloid imaging in Alzheimer's released

Only recently has it become possible to create high-quality images of the brain plaques characteristic of Alzheimer's disease in living people through positron emission tomography (PET). Even so, questions remain about what ...

Alzheimer's disease & dementia created Jan 28, 2013 | popularity not rated yet | comments 0

Binge drinking can dramatically amplify damage to the liver

Alcoholic liver disease (ALD) is characterized by a fatty liver, hepatitis, fibrosis, and cirrhosis. Binge drinking is on the rise worldwide, and is particularly common in the U.S. A review of studies addressing the effects ...

Addiction created Jan 22, 2013 | popularity not rated yet | comments 0

Eating asparagus may prevent a hangover, study finds

Drinking to ring in the New Year may leave many suffering with the dreaded hangover. According to a 2009 study in the Journal of Food Science, published by the Institute of Food Technologists (IFT), the amino acids and mi ...

Health created Jan 03, 2013 | popularity not rated yet | comments 1


Alcoholism is a broad term for problems with alcohol, and is generally used to mean compulsive and uncontrolled consumption of alcoholic beverages, usually to the detriment of the drinker's health, personal relationships, and social standing. It is medically considered a disease, specifically a neurological disorder, and in medicine several other terms are used, specifically "alcohol abuse" and "alcohol dependence" which have more specific definitions. In 1979 an expert World Health Organization committee discouraged the use of "alcoholism" in medicine, preferring the category of "alcohol dependence syndrome". In the 19th and early 20th centuries, alcohol dependence in general was called dipsomania, but that term now has a much more specific meaning. People suffering from alcoholism are often called "alcoholics". Many other terms, some of them insulting or informal, have been used throughout history. The World Health Organization estimates that there are 140 million people with alcoholism worldwide.

Alcoholism is called a "dual disease" since it includes both mental and physical components. The biological mechanisms that cause alcoholism are not well understood. Social environment, stress, mental health, family history, age, ethnic group, and gender all influence the risk for the condition. Long-term alcohol abuse produces changes in the brain's structure and chemistry such as tolerance and physical dependence. These changes maintain the person with alcoholism's compulsive inability to stop drinking and result in alcohol withdrawal syndrome if the person stops. Alcohol damages almost every organ in the body, including the brain. The cumulative toxic effects of chronic alcohol abuse can cause both medical and psychiatric problems.

Identifying alcoholism is difficult because of the social stigma associated with the disease that causes people with alcoholism to avoid diagnosis and treatment for fear of shame or social consequences. The evaluation responses to a group of standardized questioning is a common method for diagnosing alcoholism. These can be used to identify harmful drinking patterns, including alcoholism. In general, problem drinking is considered alcoholism when the person continues to drink despite wanting to stop because of social or health problems caused by drinking.

Treatment of alcoholism takes several steps. Because of the medical problems that can be caused by withdrawal, alcohol detoxification is carefully controlled and may involve medications such as benzodiazepines such as diazepam (Valium). People with alcoholism also sometimes have other addictions, including addictions to benzodiazepines, which may complicate this step. After detoxification, other support such as group therapy or self-help groups are used to help the person remain sober. Thombs (1999) states according to behavioural sciences alcoholism is described as a “maladaptive behaviour”. He explains this must not be confused with “misbehaviour”. Behavioural scientists explain that addicts have a behaviour pattern that may lead to destructive consequences for themselves, their families and society. This does not label addicts as bad or irresponsible. Compared with men, women are more sensitive to alcohol's harmful physical, cerebral, and mental effects.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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