Medical research

Alterations to gut mucus may trigger ulcerative colitis

Ulcerative colitis is the most common type of inflammatory bowel disease, characterized by chronic ulcers and inflammation in the colon and rectum. Symptoms can be lifelong and range from mild to life-threatening. There is ...

Inflammatory disorders

Researchers discover new drug target for inflammatory bowel disease

A set of interacting molecules in immune cells of the gut is responsible for preventing the inflammation seen in inflammatory bowel diseases (IBD), UT Southwestern researchers report in a new study. The findings, published ...

Immunology

In colitis patients, skin conditions may originate in the gut

A new study by UC San Francisco researchers reveals how gut inflammation can disrupt not only the digestive system, but also the skin. It's a tale in which the main players are specialized immune cells and the bacterial communities—called ...

Genetics

Exploring autoimmunity's regulatory roots

Our genome contains vast networks that regulate the activity of protein-coding genes. Variations in this regulatory DNA (which does not encode proteins) may affect both when and how much of a given protein a cell produces. ...

Immunology

Deciphering gut microbiome 'chatter' to combat IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms. Crohn's Disease and Ulcerative ...

page 4 from 40