Epilepsy

Less tau reduces seizures and sudden death in severe epilepsy

Deleting or reducing expression of a gene that carries the code for tau, a protein associated with Alzheimer's disease, can prevent seizures in a severe type of epilepsy linked to sudden death, said researchers at Baylor ...

Neuroscience created Jan 22, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

TB drug shortages put U.S. patients in peril, study finds

(HealthDay)—Shortages of key tuberculosis drugs are posing a real hazard to patients throughout the United States, a new report finds.

Diseases, Conditions, Syndromes created Jan 17, 2013 | popularity not rated yet | comments 0

Migraine sufferers stigmatized because of their condition: study

(HealthDay)—People who suffer from frequent migraines are stigmatized in much the same way as people with epilepsy are, new research suggests.

Diseases, Conditions, Syndromes created Jan 17, 2013 | popularity 5 / 5 (1) | comments 0

Childhood vaccine schedule is safe, report says

(HealthDay)—The standard vaccine schedule for young children in the United States is safe and effective, a new review says.

Medications created Jan 16, 2013 | popularity not rated yet | comments 0 | with audio podcast

Robot allows 'remote presence' in programming brain and spine stimulators

With the rapidly expanding use of brain and spinal cord stimulation therapy (neuromodulation), new "remote presence" technologies may help to meet the demand for experts to perform stimulator programming, reports a study ...

Surgery created Jan 16, 2013 | popularity not rated yet | comments 0

Discovery that some seizures arise in glial cells could offer new targets for epilepsy treatment

Epileptic seizures occur when neurons in the brain become excessively active. However, a new study from MIT neuroscientists suggests that some seizures may originate in non-neuronal cells known as glia, which ...

Neuroscience created Jan 16, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

25 new autism-related gene variants discovered

Genetics researchers have identified 25 additional copy number variations (CNVs)—missing or duplicated stretches of DNA—that occur in some patients with autism. These CNVs, say the researchers, are "high impact": although ...

Genetics created Jan 14, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Protein identified that can disrupt embryonic brain development and neuron migration

Interneurons – nerve cells that function as 'dimmers' – play an important role in the brain. Their formation and migration to the cerebral cortex during the embryonic stage of development is crucial to ...

Neuroscience created Jan 14, 2013 | popularity not rated yet | comments 0

What is deja vu and why does it happen?

Have you ever experienced a sudden feeling of familiarity while in a completely new place? Or the feeling you've had the exact same conversation with someone before?

Psychology & Psychiatry created Jan 11, 2013 | popularity 5 / 5 (3) | comments 0

How the brain stays receptive: Channel protein Pannexin1 is critical for memory and orientation

The channel protein Pannexin1 keeps nerve cells flexible and thus the brain receptive for new knowledge. Together with colleagues from Canada and the U.S., researchers at the Ruhr-Universität Bochum led by the junior professor ...

Neuroscience created Jan 09, 2013 | popularity not rated yet | comments 0

All in the family: A genetic link between epilepsy and migraine

New research reveals a shared genetic susceptibility to epilepsy and migraine. Findings published in Epilepsia, a journal of the International League Against Epilepsy (ILAE), indicate that having a strong family history of sei ...

Neuroscience created Jan 07, 2013 | popularity not rated yet | comments 0 | with audio podcast

Mild brain cooling after head injury prevents epileptic seizures in lab study

(Medical Xpress)—Mild cooling of the brain after a head injury prevents the later development of epileptic seizures, according to an animal study reported this month in the  Annals of Neurology.

Neuroscience created Dec 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researcher expects improvements to epilepsy diagnosis and prevention of life-threatening seizures

(Medical Xpress)—The electroencephalogram (EEG) for human uses has been around since 1924. Small metal discs placed along the scalp measure electrical activity in the human brain, important in diagnosing ...

Neuroscience created Dec 21, 2012 | popularity not rated yet | comments 0

How the common fruit fly is helping scientists to study alcohol-related disorders

Scientists have shown how the common fruit fly Drosophila, which possess similar electrophysiological and pharmacological properties as humans, could now be used to screen and develop new therapies for alcohol-related ...

Medical research created Dec 20, 2012 | popularity not rated yet | comments 0

High-throughput sequencing shows potentially hundreds of gene mutations related to autism

Genomic technology has revolutionized gene discovery and disease understanding in autism, according to an article published in the December 20 issue of the journal Neuron.

Genetics created Dec 19, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast


Epilepsy (from the Ancient Greek ἐπιληψία (epilēpsía) — "seizure") is a common and diverse set of chronic neurological disorders characterized by seizures. Some definitions of epilepsy require that seizures be recurrent and unprovoked, but others require only a single seizure combined with brain alterations which increase the chance of future seizures.

Epileptic seizures result from abnormal, excessive or hypersynchronous neuronal activity in the brain. About 50 million people worldwide have epilepsy, and nearly 90% of epilepsy occurs in developing countries. Epilepsy becomes more common as people age. Onset of new cases occur most frequently in infants and the elderly. As a consequence of brain surgery, epileptic seizures may occur in recovering patients.

Epilepsy is usually controlled, but not cured, with medication. However, over 30% of people with epilepsy do not have seizure control even with the best available medications. Surgery may be considered in difficult cases. Not all epilepsy syndromes are lifelong – some forms are confined to particular stages of childhood. Epilepsy should not be understood as a single disorder, but rather as syndromic with vastly divergent symptoms, all involving episodic abnormal electrical activity in the brain and numerous seizures.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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