Hepatocellular Carcinoma
Immortality gene mutation identifies brain tumors, other cancers
Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...
Cancer
Mar 18, 2013 |
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Deadly liver cancer may be triggered by cells changing identity, study shows
A rare type of cancer thought to derive from cells in the bile ducts of the liver may actually develop when one type of liver cell morphs into a totally different type, a process scientists used to consider all but impossible. ...
Cancer
Jul 16, 2012 |
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Common anti-inflammatory coaxes liver cancer cells to commit suicide
The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.
Cancer
May 16, 2011 |
4.3 / 5 (6) |
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Cancers don't sleep: The Myc oncogene can disrupt circadian rhythm
The Myc oncogene can disrupt the 24-hour internal rhythm in cancer cells. Postdoctoral fellow Brian Altman, PhD, and graduate student Annie Hsieh, MD, both from the in the lab of Chi Van Dang, MD, PhD, director of the Abramson ...
Cancer
Apr 09, 2013 |
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Sustained virological response linked with improved survival for patients with chronic HCV infection
Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with ...
Diseases, Conditions, Syndromes
Dec 25, 2012 |
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A novel oncogenic network specific to liver cancer initiation
Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, ...
Cancer
Oct 07, 2012 |
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Blocking tumor-induced inflammation impacts cancer development
Researchers at the University of California, San Diego School of Medicine report the discovery of microbial–dependent mechanisms through which some cancers mount an inflammatory response that fuels their ...
Cancer
Oct 03, 2012 |
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Liver cancer cells stop making glucose as they become cancerous
As liver cancer develops, tumor cells lose the ability to produce and release glucose into the bloodstream, a key function of healthy liver cells for maintaining needed blood-sugar levels.
Cancer
Jul 30, 2012 |
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miR-122: Loss of tiny liver molecule might lead to liver cancer
A new study shows that loss of a small RNA molecule in liver cells might cause liver cancer and that restoring the molecule might slow tumor growth and offer a new way to treat the disease.
Medical research
Jul 23, 2012 |
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Commonly used diabetes drug may help to prevent primary liver cancer
Metformin, a drug widely used to treat Type II diabetes, may help to prevent primary liver cancer, researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center report in the April 2012 issue of Cancer Pr ...
Cancer
Apr 01, 2012 |
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New compound discovered that rapidly kills liver cancer
Scientists have identified a new compound that rapidly kills hepatocellular carcinoma (HCC) cells, the most common form of liver cancer and fifth most common cancer worldwide, while sparing healthy tissue. The compound, Factor ...
Cancer
Mar 14, 2012 |
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Combining therapies appears safe, may benefit patients with advanced liver cancer
(Medical Xpress) -- Few treatments exist for patients with advanced primary liver cancer, but University of Florida researchers have found a new way to broaden the range of options and potentially improve health outcomes ...
Cancer
Jul 06, 2011 |
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Genetic variant linked to development of liver cancer in hepatitis C virus carriers
A genome-wide study by researchers at the RIKEN Center for Genomic Medicine, Hiroshima University Hospital and Sapporo-Kosei General Hospital has identified a genetic variant associated with the development ...
Genetics
Jul 03, 2011 |
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A gene that fights cancer, but causes it too
An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in ...
Cancer
May 16, 2011 |
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HIV no barrier to getting liver transplant, study finds
(HealthDay)—Liver transplants to treat a common type of liver cancer are a viable option for people infected with HIV, according to new research.
HIV & AIDS
May 17, 2013 |
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Hepatocellular carcinoma (HCC, also called malignant hepatoma) is the most common type of liver cancer. Most cases of HCC are secondary to either a viral hepatitide infection (hepatitis B or C) or cirrhosis (alcoholism being the most common cause of hepatic cirrhosis).
Compared to other cancers, HCC is quite a rare tumor in the United States. In countries where hepatitis is not endemic, most malignant cancers in the liver are not primary HCC but metastasis (spread) of cancer from elsewhere in the body, e.g., the colon. Treatment options of HCC and prognosis are dependent on many factors but especially on tumor size and staging. Tumor grade is also important. High-grade tumors will have a poor prognosis, while low-grade tumors may go unnoticed for many years, as is the case in many other organs, such as the breast, where a ductal carcinoma in situ (or a lobular carcinoma in situ) may be present without any clinical signs and without correlate on routine imaging tests, although in some occasions it may be detected on more specialized imaging studies like MR mammography.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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