Human African Trypanosomiasis
Awakening to new drugs against sleeping sickness
Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this ...
Cancer
May 17, 2013 |
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Gene clue to drug resistance in African sleeping sickness
(Medical Xpress) -- Researchers have identified a gene that controls susceptibility to drug treatment in Trypanosoma brucei, the parasite responsible for African sleeping sickness.
Diseases, Conditions, Syndromes
Jun 19, 2012 |
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Scientists take a step towards better sleeping sickness treatment
(Medical Xpress) -- Scientists at the University of Glasgow have taken a major step forward in the quest to develop new, safer drugs for the treatment of sleeping sickness.
Diseases, Conditions, Syndromes
Apr 25, 2012 |
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Old drug shows new promise to treat leishmaniasis
(Medical Xpress) -- A study published yesterday shows that a drug called fexinidazole could potentially be used to treat visceral leishmaniasis, a parasitic disease that kills 50 000 to 60 000 people ...
Diseases, Conditions, Syndromes
Feb 02, 2012 |
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Genetic technique brings new hope for better treatments for sleeping sickness
Research led by scientists at the London School of Hygiene & Tropical Medicine has exploited a revolutionary genetic technique to discover how human African Trypanosomiasis (HAT) drugs target the parasite which causes the ...
Genetics
Jan 25, 2012 |
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Wild animals may contribute to the resurgence of African sleeping sickness
Wild animals may be a key contributor to the continuing spread of African sleeping sickness, new research published in PLOS Computational Biology shows. The West African form of the disease, also known as Gambiense Human ...
Diseases, Conditions, Syndromes
Jan 17, 2013 |
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New oral drug candidate for African sleeping sickness
A new oral-only treatment for sleeping sickness has entered Phase II/III clinical study in patients with late-stage sleeping sickness in the Democratic Republic of the Congo (DRC) and soon in Central African Republic (CAR). ...
Medications
Dec 06, 2012 |
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Neglected tropical diseases: A new handle on old problems
‘Neglected tropical diseases’ is a new name for old diseases that cause long-term suffering among the world’s poorest people. The Wellcome Trust and others have funded research into these diseases ...
Diseases, Conditions, Syndromes
Jan 06, 2012 |
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Major advance in sleeping sickness drug made by Glasgow scientists
A new study published in the open-access journal PLoS Neglected Tropical Diseases on September 6th presents a key advance in developing a safer cure for sleeping sickness. Led by Professor Peter Kennedy, researchers at the ...
Medical research
Sep 06, 2011 |
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Open access initiative reveals drug hits for deadly neglected tropical diseases
The Drugs for Neglected Diseases initiative (DNDi) and Medicines for Malaria Venture (MMV) announce today the identification of three chemical series targeting the treatment of deadly neglected tropical diseases (NTDs), through ...
Diseases, Conditions, Syndromes
Nov 13, 2012 |
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First field-based molecular diagnostic test for African sleeping sickness in sight
The Geneva-based not-for-profit foundation FIND and Japanese diagnostics company Eiken announced today that a next-generation molecular test designed specifically for sleeping sickness – a deadly parasitic disease also ...
Diseases, Conditions, Syndromes
Sep 15, 2011 |
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Human African trypanosomiasis, sleeping sickness, African lethargy, or Congo trypanosomiasis is a parasitic disease of people and animals, caused by protozoa of the species Trypanosoma brucei and transmitted by the tsetse fly. The disease is endemic in some regions of sub-Saharan Africa, covering about 37 countries and 60 million people. It is estimated that 50,000 to 70,000 people are currently infected, the number having declined somewhat in recent years. The number of reported cases was below 10,000 in 2009, the first time in 50 years. It is believed that many cases go unreported. About 48,000 people died of it in 2008. Four major epidemics have occurred in recent history: one from 1896–1906 primarily in Uganda and the Congo Basin, two epidemics in 1920 and 1970 in several African countries, and a recent 2008 epidemic in Uganda.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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