Immunology

The immune cells that help tumors instead of destroying them

Lung cancer is the leading cause of cancer-associated deaths. One of the most promising ways to treat it is by immunotherapy, a strategy that turns the patient's immune system against the tumor. In the past twenty years, ...

Oncology & Cancer

Deadly lung cancers are driven by multiple genetic changes

A new UC San Francisco-led study challenges the dogma in oncology that most cancers are caused by one dominant "driver" mutation that can be treated in isolation with a single targeted drug. Instead, the new research finds ...

Oncology & Cancer

Possible new immune therapy target in lung cancer

A study from Bern University Hospital in collaboration with the University of Bern shows that so-called perivascular-like cells from lung tumors behave abnormally. They not only inadequately support vascular structures, but ...

Oncology & Cancer

Study challenges long-standing concept in cancer metabolism

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.

Oncology & Cancer

Prototype drug uses novel mechanism to treat lung cancers

Cells are constantly turning proteins on and off via molecular switches—phosphate molecules—that have become common drug targets. in a new study, lung cancer tumors were prevented in mice by a novel small molecule that ...

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