Necrosis
Simponi approved for ulcerative colitis
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Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway
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Apr 29, 2013 |
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Use of biologic therapies for inflammatory diseases does not appear to increase risk of shingles
Patients with rheumatoid arthritis (RA) who initiated use of anti-tumor necrosis factor therapies were not at a higher risk of developing herpes zoster (shingles), compared with patients who initiated nonbiologic ...
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Medications used to treat rheumatoid arthritis may affect abortion rate in women
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Apr 16, 2013 |
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Immune response linked to key enzyme
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Apr 12, 2013 |
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Cell-destroyer that fights and promotes TB reveals what's behind its split identity
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Apr 11, 2013 |
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Researchers probe the enigma of healing element that is also the enemy
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Apr 03, 2013 |
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CMV-linked eye infections ID'd in patients without HIV
(HealthDay)—Cytomegalovirus (CMV)-associated posterior uveitis or panuveitis can develop in patients without HIV infection, most of whom have evidence of compromised immune function, according to a study ...
Ophthalmology
Mar 18, 2013 |
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Same signaling enzymes can trigger two different processes in the cell
Stroke, heart attacks and numerous other common disorders result in a massive destruction of cells and tissues called necrosis. It's a violent event: As each cell dies, its membrane ruptures, releasing substances that trigger ...
Immunology
Mar 18, 2013 |
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Study advances fight against leading infectious cause of congenital birth defects
A virus most people probably have never heard of, but that the majority of us carry, is the No. 1 infectious cause of congenital birth defects in the U.S. today. Because of cytomegalovirus (CMV) infection during in utero ...
Medical research
Mar 13, 2013 |
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Magnet ingestion by young children serious and growing problem
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Pediatrics
Mar 11, 2013 |
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Use of certain therapies for inflammatory diseases does not appear to increase risk of shingles
Although patients with rheumatoid arthritis (RA) have a disproportionately higher incidence of herpes zoster (shingles), an analysis that included nearly 60,000 patients with RA and other inflammatory diseases found that ...
Inflammatory disorders
Mar 05, 2013 |
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Necrosis (from the Greek νεκρός, "dead", νέκρωσις, "death, the stage of dying, the act of killing") is the premature death of cells in living tissue. Necrosis is caused by factors external to the cell or tissue, such as infection, toxins, or trauma. This is in contrast to apoptosis, which is a naturally occurring cause of cellular death. While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental and can be fatal.
Cells that die due to necrosis do not usually send the same chemical signals to the immune system that cells undergoing apoptosis do. This prevents nearby phagocytes from locating and engulfing the dead cells, leading to a build-up of dead tissue and cell debris at or near the site of the cell death. For this reason, it is often necessary to remove necrotic tissue surgically, a process known as debridement.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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