Necrosis

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All cells need nutrients, but cancer cells are notoriously power hungry. As a result, cancer cells must alter their metabolism to provide the additional fuel needed for them to survive, grow and spread.

Feb 03, 2016
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How crystals precipitate cell death

Crystal formation plays a defining role in the pathogenesis of a range of common diseases, such as gout and atherosclerosis. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Hans-Joachim Anders have now ...

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Prognostic biomarkers ID'd in pulmonary hypertension

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Cell harm seen in lab tests of e-cigarettes

Adding to growing evidence on the possible health risks of electronic cigarettes, a lab team at the Veterans Affairs San Diego Healthcare System tested two products and found they damaged cells in ways that could lead to ...

Dec 28, 2015
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Necrosis (from the Greek νεκρός, "dead", νέκρωσις, "death, the stage of dying, the act of killing") is the premature death of cells in living tissue. Necrosis is caused by factors external to the cell or tissue, such as infection, toxins, or trauma. This is in contrast to apoptosis, which is a naturally occurring cause of cellular death. While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental and can be fatal.

Cells that die due to necrosis do not usually send the same chemical signals to the immune system that cells undergoing apoptosis do. This prevents nearby phagocytes from locating and engulfing the dead cells, leading to a build-up of dead tissue and cell debris at or near the site of the cell death. For this reason, it is often necessary to remove necrotic tissue surgically, a process known as debridement.

This text uses material from Wikipedia licensed under CC BY-SA

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