Non Small Cell Lung Cancer

New drug may help immune system fight cancer

(HealthDay)—An experimental drug that taps the power of the body's immune system to fight cancer is shrinking tumors in patients for whom other treatments have failed, an early study shows.

Cancer created May 16, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

First prospective trial shows molecular profiling timely for tailoring therapy

A clinical trial has shown that patients, and their physicians, are eager to jump into next-era cancer care—analysis of an individual's tumor to find and target genetic mutations that drive the cancer. Results of the study, ...

Cancer created May 15, 2013 | popularity not rated yet | comments 0

FDA approves genetic test for lung cancer drug

The Food and Drug Administration says it approved a genetic test from Roche to help doctors identify patients who can benefit from a lung cancer drug made by Genentech.

Medications created May 14, 2013 | popularity not rated yet | comments 0

Experimental drug beneficial in NIH trial to treat a rare sarcoma

(Medical Xpress)—Patients with advanced alveolar soft part sarcoma (ASPS), a rare cancer, achieved some control of their disease using an experimental anti-cancer drug called cediranib. The results from ...

Cancer created May 07, 2013 | popularity not rated yet | comments 0

Researchers describe how breast cancer cells acquire drug resistance

A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...

Cancer created May 07, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Diabetes drug makes lung cancer vulnerable to radiotherapy

The diabetes drug metformin slows the growth of lung cancer cells and makes them more likely to be killed by radiotherapy, according to a study published in the British Journal of Cancer today.

Cancer created May 01, 2013 | popularity 5 / 5 (2) | comments 0

Chemo, radiation followed by surgery improves survival in lung cancer patients

In one of the largest observational studies of its kind, researchers report that a combination of chemotherapy and radiation followed by surgery in patients with stage 3 non-small cell lung cancer improves survival.

Cancer created Apr 30, 2013 | popularity not rated yet | comments 0

Latest research shows two items are key to decrease symptoms and prolong survival for LMC patients

Lung cancer is one of the most common primary cancers that cause leptomeningeal carcinomatosis (LMC), when cancer spreads to the membranes surrounding the spinal cord and brain. Cases of LMC have increased because of the ...

Cancer created Apr 22, 2013 | popularity not rated yet | comments 0

Study suggests patients with lung cancer who carry specific HER2 mutations may benefit from certain anti-HER2 treatments

New results from a retrospective study conducted in Europe suggest that anti-HER2 treatments, like the widely used breast cancer agent trastuzumab (Herceptin), have anti-cancer effects in a small subset of patients with advanced ...

Cancer created Apr 22, 2013 | popularity not rated yet | comments 0

Researchers find some lung cancers linked to common virus

A common virus known to cause cervical and head and neck cancers may also trigger some cases of lung cancer, according to new research presented by Fox Chase Cancer Center at the AACR Annual Meeting 2013 on Wednesday, April ...

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

Clinical trial results for BIND-014 presented at AACR 2013

The nanoparticle drug BIND-014 is effective against multiple solid tumors, according to results generated by the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare, and presented today at the American ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

New treatment holds promise for resistant lung cancer

A new chemotherapy regimen appears to produce minimal side effects in patients with lung cancer that has not responded to previous therapy, paving the way for additional research to determine if the new regimen also helps ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Biomarkers discovered that may help predict response to drugs targeting KRAS-mutated NSCLC

Scientists have identified biomarkers that may help predict whether patients with KRAS-mutated non-small cell lung cancer (NSCLC) will respond to concurrent treatment with an MEK inhibitor and a PI3 kinase inhibitor, a drug ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Low levels of serum bilirubin spell higher lung cancer risk for male smokers

Elevated levels of bilirubin in the blood get attention in the clinic because they often indicate that something has gone wrong with the liver. Now researchers have found that male smokers with low levels of the yellow-tinged ...

Cancer created Apr 07, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Program linked to medical oncology practice improvement

(HealthDay)—For medical oncology practices in the United States, participation in the American Society of Clinical Oncology's Quality Oncology Practice Initiative (QOPI) correlates with improvements in ...

Cancer created Apr 06, 2013 | popularity not rated yet | comments 0


Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC). As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small cell carcinoma. When possible, they are primarily treated by surgical resection with curative intent, although chemotherapy is increasingly being used both pre-operatively (neoadjuvant chemotherapy) and post-operatively (adjuvant chemotherapy).

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