Non Small Cell Lung Cancer

Racial disparities in the surgical management of non-small cell lung cancer

The surgical management of non-small cell lung cancer (NSCLC) in U.S. hospitals varies widely depending on the race of the patient, according to a new study.

Cancer created May 21, 2013 | popularity not rated yet | comments 0

New drug may help immune system fight cancer

(HealthDay)—An experimental drug that taps the power of the body's immune system to fight cancer is shrinking tumors in patients for whom other treatments have failed, an early study shows.

Cancer created May 16, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

First prospective trial shows molecular profiling timely for tailoring therapy

A clinical trial has shown that patients, and their physicians, are eager to jump into next-era cancer care—analysis of an individual's tumor to find and target genetic mutations that drive the cancer. Results of the study, ...

Cancer created May 15, 2013 | popularity not rated yet | comments 0

Researchers describe how breast cancer cells acquire drug resistance

A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...

Cancer created May 07, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Experimental drug beneficial in NIH trial to treat a rare sarcoma

(Medical Xpress)—Patients with advanced alveolar soft part sarcoma (ASPS), a rare cancer, achieved some control of their disease using an experimental anti-cancer drug called cediranib. The results from ...

Cancer created May 07, 2013 | popularity not rated yet | comments 0

FDA approves genetic test for lung cancer drug

The Food and Drug Administration says it approved a genetic test from Roche to help doctors identify patients who can benefit from a lung cancer drug made by Genentech.

Medications created May 14, 2013 | popularity not rated yet | comments 0

New lung cancer test predicts survival

In the two largest clinical studies ever conducted on the molecular genetics of lung cancer, an international team led by scientists at the University of California, San Francisco (UCSF) has demonstrated that an available ...

Cancer created Jan 26, 2012 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Researchers find new drug target for lung cancer

Drugs targeting an enzyme involved in inflammation might offer a new avenue for treating certain lung cancers, according to a new study by scientists at the Salk Institute for Biological Studies.

Cancer created Feb 16, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Cancer therapy that boosts immune system ready for wider testing

Two clinical trials led by Johns Hopkins Kimmel Cancer Center researchers in collaboration with other medical centers, testing experimental drugs aimed at restoring the immune system's ability to spot and attack cancer, have ...

Cancer created Jun 02, 2012 | popularity 4.6 / 5 (7) | comments 0 | with audio podcast

Diabetes drug makes lung cancer vulnerable to radiotherapy

The diabetes drug metformin slows the growth of lung cancer cells and makes them more likely to be killed by radiotherapy, according to a study published in the British Journal of Cancer today.

Cancer created May 01, 2013 | popularity 5 / 5 (2) | comments 0

Chemo, radiation followed by surgery improves survival in lung cancer patients

In one of the largest observational studies of its kind, researchers report that a combination of chemotherapy and radiation followed by surgery in patients with stage 3 non-small cell lung cancer improves survival.

Cancer created Apr 30, 2013 | popularity not rated yet | comments 0

Cancer breathalyzer: Researchers developing breath test for possible diagnosis of lung and breast cancers

(Medical Xpress) -- A breath test designed to detect established lung cancer in humans showed promising results in a study conducted by researchers at the Georgia Institute of Technology and the Winship Cancer ...

Cancer created Jun 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Trojan horse drug therapy provides new approach to treating breast cancer

When Linda Tuttle was diagnosed with breast cancer, she never imagined her experience would inspire her colleagues to design new treatments to tackle the disease.

Cancer created Oct 02, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Breakthrough in understanding lung cancer vulnerabilities points the way to new targeted therapy

More effective treatments for one of the deadliest forms of cancer are one step closer thanks to groundbreaking research from an international collaborative study.

Cancer created Oct 01, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

BIM gene variation in East Asians found to explain resistance to cancer drugs

A multi-national research team led by scientists at Duke-NUS Graduate Medical School has identified the reason why some patients fail to respond to some of the most successful cancer drugs.

Cancer created Mar 18, 2012 | popularity not rated yet | comments 0 | with audio podcast


Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC). As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small cell carcinoma. When possible, they are primarily treated by surgical resection with curative intent, although chemotherapy is increasingly being used both pre-operatively (neoadjuvant chemotherapy) and post-operatively (adjuvant chemotherapy).

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