Pancreatic Cancer
PARP inhibitor shows activity in pancreatic, prostate cancers among patients carrying BRCA mutations
In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced ...
Cancer
May 15, 2013 |
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Breakthrough in how pancreatic cancer cells ingest nutrients points to new drug target
In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a ...
Cancer
May 13, 2013 |
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Gastroenterology special issue highlights the pancreas
The editors of Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute, are pleased to announce the publication of this year's highly anticipated special 13th issue. Published each M ...
Diseases, Conditions, Syndromes
May 08, 2013 |
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Pioneering search for pancreatic cancer 'fingerprint' in simple blood test
Pioneering research to investigate whether pancreatic cancer can be detected early through a blood test is to be spearheaded by the University of Leicester thanks to new funding provided by Hope Against Cancer.
Cancer
Apr 23, 2013 |
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Pancreatic cancer diagnosis under review
A team of researchers of the UPV/EHU together with researchers from the Hospital Clínico of Barcelona have produced a bibliographical review that summarises the data currently existing on the markers for ...
Cancer
Apr 23, 2013 |
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Radioactive bacteria targets metastatic pancreatic cancer
Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them. The ex ...
Cancer
Apr 22, 2013 |
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Diagnosis and management of pancreatic cancer: A review for physicians
Pancreatic cancer is the fourth leading cause of death from cancer, and while family physicians in Canada only see 1 cases a year, the number of cases is expected to increase as the population ages. A review in CMAJ (Canad ...
Cancer
Apr 22, 2013 |
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Blocking 'scaffold' protein inhibits cancer growth, study finds
(Medical Xpress)—Researchers at the Stanford University School of Medicine have devised an entirely novel way to block biological signaling pathways that, when overactive, lead to many types of cancers. They've done so ...
Cancer
Apr 22, 2013 |
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Rigosertib Phase 1 results lead to disease-focused Phase 2 development
Results of a phase 1 clinical trial reported at the American Association for Cancer Research (AACR) annual conference show that orally administered Rigosertib is well tolerated in patients with advanced solid tumors. This ...
Cancer
Apr 09, 2013 |
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Scientists advance findings about novel, low-toxicity anticancer agent
(Medical Xpress)—Researchers at Roswell Park Cancer Institute (RPCI) have found that a new formulation of a promising anticancer agent, the small chemical molecule FL118, is even more effective in controlling two types ...
Cancer
Apr 03, 2013 |
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Prostate cancer risk rises in men with inherited genetic condition
Men with an inherited genetic condition called Lynch syndrome face a higher lifetime risk of developing prostate cancer and appear to develop the disease at an earlier age, according to a new study led by ...
Cancer
Apr 01, 2013 |
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New metabolite-based diagnostic test could help detect pancreatic cancer early
A new diagnostic test that uses a scientific technique known as metabolomic analysis may be a safe and easy screening method that could improve the prognosis of patients with pancreatic cancer through earlier detection.
Cancer
Mar 29, 2013 |
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Scientists find potential loophole in pancreatic cancer defenses
Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control ...
Cancer
Mar 27, 2013 |
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Researchers help test cancer drug in clinical trial leading to FDA approval
The FDA has approved a thyroid cancer drug successfully tested at Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and the Translational Genomics Research Institute (TGen).
Cancer
Mar 27, 2013 |
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Research suggests popular diabetes drugs can cause abnormal pancreatic growth in humans
(Medical Xpress)—Individuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine ...
Diabetes
Mar 27, 2013 |
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Pancreatic cancer refers to a malignant neoplasm originating from transformed cells arising in tissues forming the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors, is adenocarcinoma (tumors exhibiting glandular architecture on light microscopy) arising within the exocrine component of the pancreas. A minority arise from islet cells, and are classified as neuroendocrine tumors. The symptoms that lead to diagnosis depend on the location, the size, and the tissue type of the tumor. They may include abdominal pain and jaundice (if the tumor compresses the bile duct).
Pancreatic cancer is the fourth most common cause of cancer death across the globe. Pancreatic cancer often has a poor prognosis: for all stages combined, the 1- and 5-year relative survival rates are 25% and 6%, respectively; for local disease the 5-year survival is approximately 20% while the median survival for locally advanced and for metastatic disease, which collectively represent over 80% of individuals, is about 10 and 6 months respectively.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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