Peripheral Arterial Disease

Drug sharply lowers cholesterol in animal tests

An Arizona drug company will patent a small peptide—developed through research at the University of Alabama at Birmingham—that shows significant ability to lower blood cholesterol in animal models. Capstone Therapeutics ...

Aug 07, 2015
popularity75 comments 0

Peripheral vascular disease (PVD), commonly referred to as peripheral arterial disease (PAD) or peripheral artery occlusive disease (PAOD), refers to the obstruction of large arteries not within the coronary, aortic arch vasculature, or brain. PVD can result from atherosclerosis, inflammatory processes leading to stenosis, an embolism, or thrombus formation. It causes either acute or chronic ischemia (lack of blood supply). Often PAD is a term used to refer to atherosclerotic blockages found in the lower extremity.

PVD also includes a subset of diseases classified as microvascular diseases resulting from episodal narrowing of the arteries (Raynaud's phenomenon), or widening thereof (erythromelalgia), i.e. vascular spasms.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Study reveals the genetic start-up of a human embryo

An international team of scientists led from Sweden's Karolinska Institutet has for the first time mapped all the genes that are activated in the first few days of a fertilized human egg. The study, which is being published ...

New mechanism discovered behind infant epilepsy

Scientists at Karolinska Institutet and Karolinska University Hospital in Sweden have discovered a new explanation for severe early infant epilepsy. Mutations in the gene encoding the protein KCC2 can cause the disease, hereby ...

Neuron responsible for alcoholism found

Scientists have pinpointed a population of neurons in the brain that influences whether one drink leads to two, which could ultimately lead to a cure for alcoholism and other addictions.