Peripheral Arterial Disease

Peripheral vascular disease (PVD), commonly referred to as peripheral arterial disease (PAD) or peripheral artery occlusive disease (PAOD), refers to the obstruction of large arteries not within the coronary, aortic arch vasculature, or brain. PVD can result from atherosclerosis, inflammatory processes leading to stenosis, an embolism, or thrombus formation. It causes either acute or chronic ischemia (lack of blood supply). Often PAD is a term used to refer to atherosclerotic blockages found in the lower extremity.

PVD also includes a subset of diseases classified as microvascular diseases resulting from episodal narrowing of the arteries (Raynaud's phenomenon), or widening thereof (erythromelalgia), i.e. vascular spasms.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Gut bacteria promote obesity in mice

A species of gut bacteria called Clostridium ramosum, coupled with a high-fat diet, may cause animals to gain weight. The work is published this week in mBio, the online open-access journal of the American Society for Microbiol ...

Researchers explain 38-year-old mystery of the heart

In a new study published in Proceedings of the National Academy of Sciences, researchers at the University of Alberta's Faculty of Medicine & Dentistry have explained how the function of a key protein in the ...

Modeling shockwaves through the brain

Since the start of the military conflicts in Iraq and Afghanistan, more than 300,000 soldiers have returned to the United States with traumatic brain injury caused by exposure to bomb blasts—and in particular, ...