Genetics
Cellular repair could reduce premature aging
Researchers have identified a potential drug therapy for a premature ageing disease that affects children causing them to age up to eight times as fast as the usual rate.
Nov 2, 2011
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Progeria
Medical research
Scientists investigate new strategy to treat spinal muscular atrophy in infants
Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic ...
May 8, 2018
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75
Genetics
Researchers describe mechanism behind progeria
Progeria, a premature aging disease, is the research focus of Roland Foisner's team at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna. Children suffering from progeria die ...
Oct 6, 2015
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603
Medical research
Safe, inexpensive chemical found to reverse symptoms of progeria in human cells
Progeria is a rare genetic disease that mimics the normal aging process at an accelerated rate. Symptoms typically appear within the first year of life, and individuals with the disease develop thin, wrinkled skin, fragile ...
Dec 10, 2015
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154
Genetics
A new genome editing method brings the possibility of gene therapies closer to reality
Researchers from Salk Institute for Biological Studies, BGI, and other institutes for the first time evaluated the safety and reliability of the existing targeted gene correction technologies, and successfully developed a ...
Jul 11, 2014
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Medical research
Protein turnover could be clue to living longer
It may seem paradoxical, but studying what goes wrong in rare diseases can provide useful insights into normal health. Researchers probing the premature aging disorder Hutchinson-Gilford progeria have uncovered an errant ...
Aug 30, 2017
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15
Diseases, Conditions, Syndromes
Progeria: First-ever treatment for rare childhood aging disease shows improvement in all trial participants
Results of the first-ever clinical drug trial for children with Progeria, a rare, fatal "rapid-aging" disease, demonstrate the efficacy of a farnesyltransferase inhibitor (FTI), a drug originally developed to treat cancer. ...
Sep 24, 2012
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0
Medical research
Possible new treatment strategy against progeria
Progeria is a very rare disease that affects about one in 18 million children and results in premature aging and death in adolescence from complications of cardiovascular disease. In a study on mice and human cells, researchers ...
Nov 18, 2019
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107
Genetics
DNA-editing method shows promise to treat mouse model of progeria
Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature aging in children and can ...
Jan 6, 2021
15
63
Medical research
Mouse study identifies new target for human accelerated aging syndrome
Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterised by premature ageing.
Apr 27, 2018
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