Immunology

Gut microbes trigger autoimmune disease later in life in mice

Researchers have revealed that the colonization of the gut of young mice by certain types of bacteria can lead to immune responses later in life that are linked to disease. Increases in the levels of segmented filamentous ...

Diseases, Conditions, Syndromes

Flipping the switch on scleroderma

Scleroderma is a rare and often fatal disease, causing the thickening of tissue, that currently lacks a cure and any effective treatments. A group of researchers, including a Michigan State University professor, is looking ...

Diseases, Conditions, Syndromes

Biomarker identified in systemic sclerosis predicts progression

(HealthDay)—Patients with systemic sclerosis have elevated levels of CXCL4, which predicts disease risk and progression, according to a study published online Dec. 18 in the New England Journal of Medicine.

Diseases, Conditions, Syndromes

New treatment for disfiguring skin condition

Researchers from The University of Manchester and Salford Royal NHS Foundation Trust have tested a new way to treat a disfiguring skin condition.

Arthritis & Rheumatism

Updated systemic sclerosis criteria improve disease classification

New classification criteria for systemic sclerosis have just been published and are more sensitive than the 1980 criteria, enabling earlier identification and treatment of this disabling autoimmune disease. The 2013 criteria, ...

Diseases, Conditions, Syndromes

Genes reveal which patients will benefit from scleroderma drug

Systemic sclerosis, also known as scleroderma, is a rare autoimmune connective tissue disorder that's difficult to treat. However, thanks to new research at Northwestern University Feinberg School of Medicine and Dartmouth's ...

Diseases, Conditions, Syndromes

AAD: Skin changes can be first sign of underlying condition

(HealthDay)—Skin changes, including new rash, new growths, discoloration, and changes in texture, could be among the first signs indicating an underlying medical condition, according to information presented at the annual ...

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