Diseases, Conditions, Syndromes

Rapid test delineates diseases with similar symptoms

Malaria and typhoid fever are major health problems in tropical regions, but accurate diagnosis is often hampered by overlapping or nonspecific symptoms and limited access to diagnostics. Now, NIBIB-funded scientists have ...

Medical research

Study finds key mechanism for how typhoid bacteria infects

A new study has uncovered key details for how the Salmonella bacteria that causes typhoid fever identifies a host's immune cells and delivers toxins that disrupt the immune system and allow the pathogen to spread.

page 1 from 5

Typhoid fever, also known as Typhoid, is a common worldwide bacterial disease, transmitted by the ingestion of food or water contaminated with the feces of an infected person, which contain the bacterium Salmonella enterica, serovar Typhi. The bacteria then perforate through the intestinal wall and are phagocytosed by macrophages The organism is a Gram-negative short bacillus that is motile due to its peritrichous flagella. The bacterium grows best at 37°C / 98.6°F – human body temperature.

This fever received various names, such as gastric fever, abdominal typhus, infantile remittant fever, slow fever, nervous fever, pythogenic fever, etc. The name of "typhoid" comes from the neuropsychiatric symptoms common to typhoid and typhus (from Greek τῦϕος, "stupor").

The impact of this disease fell sharply with the application of modern sanitation techniques.

This text uses material from Wikipedia licensed under CC BY-SA