A new preclinical candidate drug with the potential to treat visceral leishmaniasis, one of the world's major neglected diseases, has been discovered through a close collaboration between the University of Dundee, GSK and ...
Jul 25, 2018
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One form of the disease begins with large open sores that won't heal, then migrates to the nose and lips, rotting them away like a form of leprosy and leaving the victim badly disfigured.
Jun 7, 2018
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In an article in the latest issue of PLOS Pathogens, INRS professor Simona Stäger and her team show how the parasite Leishmania donovani uses a physiological response to low oxygen levels (hypoxia) to establish a chronic ...
Oct 4, 2017
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Parasites that ulcerate the skin, can disfigure the face, and may fatally mutilate its victim's internal organs are creeping closer to the southern edges of the United States.
Sep 13, 2017
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Scientists at the University of York have discovered that parasites responsible for leishmaniasis - a globally occurring neglected tropical disease spread by sand flies - are mainly acquired from the skin rather than a person's ...
Jul 5, 2017
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Chemistry students are making compounds that may help treat diseases thanks to an open collaboration with the Drugs for Neglected Diseases initiative.
May 4, 2017
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This week scientists, policy makers, and other global health actors will meet in Geneva for a Summit on Neglected Tropical Diseases (NTDs)—a group of diseases that overwhelmingly affect the poorest of the poor in low- and ...
Apr 21, 2017
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Driven by burgeoning ecotourism and military campaigns in Iraq and Afghanistan, a parasitic infection called leishmaniasis is showing up in more U.S. patients, often stumping doctors. Rapid diagnostic tests and innovative ...
Nov 15, 2016
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A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered ...
Aug 25, 2016
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With an estimated 500,000 human infections and 50,000 deaths annually, visceral leishmaniasis (VL) is the second most prevalent parasitic killer, behind malaria. Leishmania parasites are transmitted through the bite of phlebotomine ...
Aug 18, 2016
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