Cell Stem Cell
Using human brain cells to make mice smarter
Glial cells – a family of cells found in the human central nervous system and, until recently, considered mere "housekeepers" – now appear to be essential to the unique complexity of the human brain. Scientists reached ...
Medical research
Mar 07, 2013 |
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Extra chromosome 21 removed from Down syndrome cell line
(Medical Xpress)—University of Washington scientists have succeeded in removing the extra copy of chromosome 21 in cell cultures derived from a person with Down syndrome, a condition in which the body's ...
Medical research
Nov 09, 2012 |
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Stem cell study: Male fertility can be restored after cancer treatment
An injection of banked sperm-producing stem cells can restore fertility to male primates who become sterile due to cancer drug side effects, according to researchers at the University of Pittsburgh School of Medicine and ...
Medical research
Nov 01, 2012 |
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About face: Long-ignored segments of DNA play role in early stages of face development
(Medical Xpress)—The human face is a fantastically intricate thing. The billions of people on the planet have faces that are individually recognizable because each has subtle differences in its folds and ...
Genetics
Oct 22, 2012 |
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Researcher discovers epigenetic links in cell-fate decisions of adult stem cells
(Medical Xpress) -- The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases.
Genetics
Jul 09, 2012 |
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Scientists correct Huntington's disease mutation in induced pluripotent stem cells
Johns Hopkins researchers, working with an international consortium, say they have generated stem cells from skin cells from a person with a severe, early-onset form of Huntington's disease (HD), and turned them into neurons ...
Medical research
Jun 28, 2012 |
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Scientists turn skin cells into brain cells
Scientists at the Gladstone Institutes have for the first time transformed skin cellswith a single genetic factorinto cells that develop on their own into an interconnected, functional network of brain cells. ...
Medical research
Jun 07, 2012 |
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Stem-cell-based strategy boosts immune system in mice
Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, ...
Immunology
May 16, 2013 |
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Human brain cells developed in lab, grow in mice
A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat ...
Medical research
May 08, 2013 |
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Gene thought to make heart tissues turns out to make blood and muscles as well
New research out of the Lillehei Heart Institute at the University of Minnesota shows that by turning on just a single gene, Mesp1, different cell types including the heart, blood and muscle can be created from stem cells.
Genetics
May 02, 2013 |
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Turning human stem cells into brain cells sheds light on neural development
Medical researchers have manipulated human stem cells into producing types of brain cells known to play important roles in neurodevelopmental disorders such as epilepsy, schizophrenia and autism. The new model cell system ...
Medical research
May 02, 2013 |
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Reinventing drug discovery: Promising drug target for ALS
Using a new stem-cell based drug screening technology with the potential to reinvent and greatly reduce the cost of the way new pharmaceuticals are developed, Harvard Stem Cell Institute (HSCI) researchers ...
Diseases, Conditions, Syndromes
Apr 18, 2013 |
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Brain development is guided by 'junk' DNA that isn't really junk
(Medical Xpress)—Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.
Genetics
Apr 15, 2013 |
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Ills of aging blood: Short-circuited stem cell programming linked to failing blood development
As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced immune ...
Medical research
Feb 15, 2013 |
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Researchers identify potential target for age-related cognitive decline
Cognitive decline in old age is linked to decreasing production of new neurons. Scientists from the German Cancer Research Center have discovered in mice that significantly more neurons are generated in the ...
Medical research
Feb 07, 2013 |
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