Cell Stem Cell

Using human brain cells to make mice smarter

Glial cells – a family of cells found in the human central nervous system and, until recently, considered mere "housekeepers" – now appear to be essential to the unique complexity of the human brain. Scientists reached ...

Medical research created Mar 07, 2013 | popularity 3.7 / 5 (3) | comments 2 | with audio podcast

Extra chromosome 21 removed from Down syndrome cell line

(Medical Xpress)—University of Washington scientists have succeeded in removing the extra copy of chromosome 21 in cell cultures derived from a person with Down syndrome, a condition in which the body's ...

Medical research created Nov 09, 2012 | popularity 4.9 / 5 (11) | comments 0 | with audio podcast

Stem cell study: Male fertility can be restored after cancer treatment

An injection of banked sperm-producing stem cells can restore fertility to male primates who become sterile due to cancer drug side effects, according to researchers at the University of Pittsburgh School of Medicine and ...

Medical research created Nov 01, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

About face: Long-ignored segments of DNA play role in early stages of face development

(Medical Xpress)—The human face is a fantastically intricate thing. The billions of people on the planet have faces that are individually recognizable because each has subtle differences in its folds and ...

Genetics created Oct 22, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Researcher discovers epigenetic links in cell-fate decisions of adult stem cells

(Medical Xpress) -- The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases.

Genetics created Jul 09, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists correct Huntington's disease mutation in induced pluripotent stem cells

Johns Hopkins researchers, working with an international consortium, say they have generated stem cells from skin cells from a person with a severe, early-onset form of Huntington's disease (HD), and turned them into neurons ...

Medical research created Jun 28, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists turn skin cells into brain cells

Scientists at the Gladstone Institutes have for the first time transformed skin cells—with a single genetic factor—into cells that develop on their own into an interconnected, functional network of brain cells. ...

Medical research created Jun 07, 2012 | popularity 5 / 5 (6) | comments 3 | with audio podcast

Stem-cell-based strategy boosts immune system in mice

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, ...

Immunology created May 16, 2013 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Human brain cells developed in lab, grow in mice

A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat ...

Medical research created May 08, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Gene thought to make heart tissues turns out to make blood and muscles as well

New research out of the Lillehei Heart Institute at the University of Minnesota shows that by turning on just a single gene, Mesp1, different cell types including the heart, blood and muscle can be created from stem cells.

Genetics created May 02, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Turning human stem cells into brain cells sheds light on neural development

Medical researchers have manipulated human stem cells into producing types of brain cells known to play important roles in neurodevelopmental disorders such as epilepsy, schizophrenia and autism. The new model cell system ...

Medical research created May 02, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Reinventing drug discovery: Promising drug target for ALS

Using a new stem-cell based drug screening technology with the potential to reinvent and greatly reduce the cost of the way new pharmaceuticals are developed, Harvard Stem Cell Institute (HSCI) researchers ...

Diseases, Conditions, Syndromes created Apr 18, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Brain development is guided by 'junk' DNA that isn't really junk

(Medical Xpress)—Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.

Genetics created Apr 15, 2013 | popularity 4.9 / 5 (14) | comments 2 | with audio podcast

Ills of aging blood: Short-circuited stem cell programming linked to failing blood development

As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced immune ...

Medical research created Feb 15, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Researchers identify potential target for age-related cognitive decline

Cognitive decline in old age is linked to decreasing production of new neurons. Scientists from the German Cancer Research Center have discovered in mice that significantly more neurons are generated in the ...

Medical research created Feb 07, 2013 | popularity 5 / 5 (2) | comments 0