Genes & Development

Medical research

Discovery illuminates how thyroid hormone 'dims' metabolism

It has been known for some time that the thyroid gland is a strong regulator of the body's metabolism, making it key to many health conditions. But the molecular details of how thyroid hormone acts on cells in the body have ...

Diseases, Conditions, Syndromes

Progress toward improved Wilson's disease drug

Researchers at Cold Spring Harbor Laboratory (CSHL), working in collaboration with DepYmed Inc., a CSHL spinout company, today report that they have conducted promising preclinical experiments on a compound that could be ...

Genetics

Novel approach reduces SCA1 symptoms in animal model

Research has shown that a mutation in the ATAXIN-1 gene leads to accumulation of Ataxin-1 (ATXN1) protein in brain cells and is the root cause of a rare genetic neurodegenerative disease known as spinocerebellar ataxia type ...

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