Journal of Biological Chemistry

DNA-repairing protein may be key to preventing recurrence of some cancers

Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...

Cancer created Jan 28, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists identify new strategy to fight deadly infection in cystic fibrosis

New research suggests that lowering excessive levels of a protein in immune system cells could be a strategy to clear an infection that is deadly to patients with cystic fibrosis (CF).

Medical research created Jan 23, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study reveals promising new target for Parkinson's disease therapies

With a new insight into a model of Parkinson's disease, researchers from the University of Pennsylvania School of Veterinary Medicine have identified a novel target for mitigating some of the disease's toll on the brain.

Parkinson's & Movement disorders created Jan 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Medicinal toothbrush tree yields antibiotic to treat TB in new way

A compound from the South African toothbrush tree inactivates a drug target for tuberculosis in a previously unseen way.

Diseases, Conditions, Syndromes created Jan 14, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists uncover potential drug target to block cell death in Parkinson's disease

Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer's disease, Amyotrophic Lateral Sclerosis and Parkinson's disease. Now, scientists from the Florida campus of ...

Parkinson's & Movement disorders created Jan 10, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Inherited retinal disease research may lead to treatment

Inherited retinal disease is a major cause of vision impairment in early life - and a researcher at The University of Western Australia hopes a study in which he was involved will contribute towards the development ...

Medical research created Jan 08, 2013 | popularity 5 / 5 (1) | comments 0

Cholesterol boosts the memory of the immune system

The memory of the human immune system is critical for the development of vaccines. Only if the body recognizes a pathogen with which it has already come into contact in the case of a second infection, the ...

Immunology created Dec 24, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Liver mitochondria improve, increase after chronic alcohol feeding in mice

(Medical Xpress)—Scientists at the Keck School of Medicine of the University of Southern California (USC) have found evidence that liver mitochondria in mice adapt to become better metabolizers of alcohol and increase in ...

Medical research created Dec 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Removing protein 'garbage' in nerve cells may help control two neurodegenerative diseases

Neuroscientists at Georgetown University Medical Center say they have new evidence that challenges scientific dogma involving two fatal neurodegenerative diseases—amyotrophic lateral sclerosis (ALS), and frontotemporal ...

Medical research created Dec 20, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Preventing deadly aortic aneurysms

(Medical Xpress)—A researcher with the University of Alberta's Faculty of Medicine & Dentistry and the Mazankowski Alberta Heart Institute is looking closely at a molecule linked to aortic aneurysms in ...

Cardiology created Dec 18, 2012 | popularity 5 / 5 (1) | comments 0

MicroRNA-218 targets medulloblastoma, most aggressive childhood brain cancer

Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the expression of faulty genes ...

Cancer created Dec 13, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New computer model to speed development of drugs for heart failure

(Medical Xpress)—Researchers at the University of Virginia have developed a new model of how the heart reacts to stresses such as high blood pressure, shedding light on a common cause of heart failure and facilitating the ...

Medical research created Dec 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers find clue to how Hepatitis C virus harms liver

Researchers at the University of Southern California (USC) have discovered a trigger by which the Hepatitis C virus enters liver cells ─ shedding light on how this serious and potentially deadly virus can begin to damage ...

Diseases, Conditions, Syndromes created Dec 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Grilled, seared foods may add to waistlines, disease risk

(Medical Xpress)—A steak slapped onto a hot barbecue will leave the meat with black grill lines that add flavor and aroma, but the chemicals contained in charred, seared and fried foods may over time kick-start ...

Medical research created Dec 12, 2012 | popularity 4 / 5 (4) | comments 2 | with audio podcast

Scientists uncover a novel cooperative effort to stop cancer spread

(Medical Xpress)—Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the ...

Cancer created Nov 28, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast