Journal of Biological Chemistry

Oncology & Cancer

The sugar-attaching enzyme that defines colon cancer

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry. The enzyme appears to drive ...

Oncology & Cancer

Researchers report a new target to treat prostate cancer

The drug Gefitinib is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer. EGFR, present on the cell membrane, ...

Genetics

Study sheds light on rarity of disease-causing IGF mutations

Peter Rotwein, M.D., was recently spotlighted by the American Society for Biochemistry and Molecular Biology (ASBMB) for a study he conducted on insulin-like growth factors (IGFs), a family of proteins that are crucial in ...

Diabetes

Pre-diabetes discovery marks step towards precision medicine

Researchers from the University of Sydney's Charles Perkins Centre have identified three specific molecules that accurately indicate insulin resistance, or pre-diabetes - a major predictor of metabolic syndrome, the collection ...

Oncology & Cancer

Microbiologists contribute to possible new anti-TB treatment path

As part of the long effort to improve treatment of tuberculosis (TB), microbiologists led by Yasu Morita at the University of Massachusetts Amherst report that they have for the first time characterized a protein involved ...

Oncology & Cancer

Cancer researchers publish new papers on ovarian cancer tumor growth

Two papers involving ovarian cancer research at the University of Notre Dame's Harper Cancer Research Institute (HCRI), one featuring new research and the other a review article, were published as cover stories in their respective ...

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