Journal of Experimental Medicine

Cardiology

Mechanism discovered that leads to ANCA-associated vasculitis

The immune system can become the enemy when mechanisms that are actually protective get out of control. In ANCA-associated vasculitis, excessive inflammatory reactions lead to pulmonary hemorrhages that can be fatal if left ...

Neuroscience

The brain's drainage system in 3D

Meningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Brain Institute (Pitié-Salpêtrière Hospital, Paris) have imaged brain drainage by meningeal lymphatics in mice ...

Medical research

Study reveals new mode of triggering immune responses

Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers ...

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