Journal of Experimental Medicine

Parkinson's disease protein causes disease spread and neuron death in healthy animals

Understanding how any disease progresses is one of the first and most important steps towards finding treatments to stop it. This has been the case for such brain-degenerating conditions as Alzheimer's disease. ...

Parkinson's & Movement disorders created Nov 15, 2012 | popularity 5 / 5 (6) | comments 1 | with audio podcast

Breakthrough in battle against leukemia

Scientists at Griffith University's Institute for Glycomics and The Saban Research Institute of Children's Hospital Los Angeles have discovered a critical weakness in leukaemic cells, which may pave the way to new treatments.

Cancer created Mar 13, 2013 | popularity 5 / 5 (5) | comments 0

Two-faced leukemia?

One kind of leukemia sometimes masquerades as another, according to a study published online this week in the Journal of Experimental Medicine.

Cancer created Dec 12, 2011 | popularity 5 / 5 (4) | comments 0

Cellular metabolism arms T cells to battle viruses and tumours

(Medical Xpress)—New research demonstrates that the cellular metabolism of certain immune cells is closely linked to their function, which includes protecting against viral infections and the development of tumours.

Medical research created Dec 24, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Hitting 'reset' in protein synthesis restores myelination, suggests new treatment for misfolded protein diseases

(Medical Xpress)—A potential new treatment strategy for patients with Charcot-Marie-Tooth disease is on the horizon, thanks to research by neuroscientists now at the University at Buffalo's Hunter James ...

Medical research created Apr 26, 2013 | popularity 4.3 / 5 (4) | comments 0 | with audio podcast

Loss of weight associated with chronic illness may soon have first treatment

Patients with cancer, heart disease and other chronic illness struggle not only with complications inherent to their disease, they also experience an involuntary loss of weight and muscle mass triggered by ...

Medical research created Nov 15, 2011 | popularity 5 / 5 (3) | comments 0

Scientists link 'oncometabolite' to onset of acute myeloid leukemia

A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme ...

Cancer created Jul 04, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Gene knockout stops immune cell development

(Medical Xpress)—Researchers at the Wellcome Trust Sanger Institute have identified the key gene in ensuring that our immune defences develop infection-fighting cells. No cells of the adaptive immune system ...

Immunology created Dec 11, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Evolution in the antibody factory: How immune cells are able to advance their own evolution

Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy. They concurrently and continuously improve ...

Immunology created Mar 11, 2013 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Molecule treats leukemia by preventing cancer cell repair, scientists report

(Medical Xpress)—Researchers at The Jackson Laboratory have identified a molecule that prevents repair of some cancer cells, providing a potential new "genetic chemotherapy" approach to cancer treatment ...

Cancer created Apr 17, 2013 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Scientists identify a novel therapy with potential for treating Parkinson's disease

Scientists at the University of Cambridge have made a significant step in the development of a novel therapy that could one day help to slow down, or even halt, the damage caused by Parkinson’s disease ...

Medical research created Dec 22, 2011 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Drug combination domino effect destroys pancreatic cancer cells

(Medical Xpress) -- Cancer Research UK scientists have revealed how a combination of two very different drugs – currently being tested in clinical trials – amplifies the destruction of pancreatic cancer cells, according ...

Cancer created Feb 22, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Getting down to the heart of the (gray) matter to treat Parkinson's disease

An agent under consideration for use in PET imaging combats neuronal death to relieve Parkinsonian symptoms in animal models, according to a study published on April 2nd in the Journal of Experimental Medicine.

Parkinson's & Movement disorders created Apr 02, 2012 | popularity 5 / 5 (2) | comments 0

Potential gene therapy for patients with rare disease

Australian scientists have discovered that a biological phenomenon known as ‘somatic reversion’, when an abnormal gene spontaneously becomes normal again, explains why some patients with a rare genetic ...

Medical research created Apr 12, 2012 | popularity 5 / 5 (2) | comments 0

CAMH protein discovery may lead to new treatment to prevent smoking relapse

Scientists at the Centre for Addiction and Mental Health (CAMH) have identified a potential new approach to preventing smoking relapse, which occurs frequently in smokers who attempt to quit, despite current treatments.

Health created Oct 22, 2012 | popularity 5 / 5 (2) | comments 0